Found 471 articles for: "retinoids"
Successful Management of a Black Male With Psoriasis and Dyspigmentation Treated With Halobetasol Propionate 0.01%/Tazarotene 0.045% Lotion: Case Report
October 2020 | Volume 19 | Issue 10 | Case Reports | 1000 | Copyright © October 2020
Skin of color patients with psoriasis face unique challenges related to disease characteristics and treatment. Dyspigmentation, including postinflammatory hypo- and hyperpigmentation, more frequently ...
Read MoreCutaneous Manifestations of EGFR-Inhibitors in African Americans and Treatment Considerations
September 2020 | Volume 19 | Issue 9 | Case Reports | 894 | Copyright © September 2020
Epidermal growth factor (EGFR)-inhibitors have emerged as the primary therapy in advanced solid tumor malignancies because of improvement in survival with overall favorable side effect profile. Howeve...
Read MoreThe Impact of COVID-19 on the Faces of Frontline Healthcare Workers
September 2020 | Volume 19 | Issue 9 | Original Article | 858 | Copyright © September 2020
As the coronavirus epidemic continues, a host of new cutaneous complications is seen on the faces of frontline healthcare workers wearing personal protective equipment on a daily basis. To minimize th...
Read MoreARTICLE: The 1440 nm and 1927 nm Nonablative Fractional Diode Laser: Current Trends and Future Directions
August 2020 | Volume 19 | Issue 8 | Supplement Individual Articles | s3 | Copyright © August 2020
Clinical characteristics of skin exposed to ultraviolet and infrared radiation include dryness, dyschromia, laxity, roughness, sallowness, scaling, telangiectasia, and wrinkles. Fractional photothermo...
Read MorePost-Inflammatory Hyperpigmentation: A Review of Treatment Strategies
August 2020 | Volume 19 | Issue 8 | Original Article | 763 | Copyright © August 2020
Post-inflammatory hyperpigmentation (PIH) is a reactive process resulting from increased melanin or abnormal distribution of melanin secondary to inflammatory skin conditions, dermatologic therapies, ...
Read MoreOral Metformin for Treating Dermatological Diseases: A Systematic Review
August 2020 | Volume 19 | Issue 8 | Original Article | 713 | Copyright © August 2020
Introduction:Metformin is an antihyperglycemic medication most commonly used to treat Type II Diabetes Mellitus with promising off-label application for the treatment of hidradenit...
Read MoreOnce-Daily Polymeric Tazarotene 0.045% Lotion for Moderate-to-Severe Acne: Pooled Phase 3 Analysis by Sex
August 2020 | Volume 19 | Issue 8 | Original Article | 777 | Copyright © August 2020
Background: Two identical phase 3 randomized, double-blind, vehicle-controlled, 12-week studies (NCT03168321 and NCT03168334) demonstrated the efficacy and safety of tazarotene 0.045%...
Read MoreRoflumilast Cream Improves Signs and Symptoms of Plaque Psoriasis: Results from a Phase 1/2a Randomized, Controlled Study
August 2020 | Volume 19 | Issue 8 | Original Article | 734 | Copyright © August 2020
Background: Roflumilast cream (ARQ-151) is a highly potent, selective phosphodiesterase-4 inhibitor in development for once-daily topical treatment of chronic plaque psoriasis.
...
Read MoreNovel Polymeric Tazarotene 0.045% Lotion for Moderate-to-Severe Acne: Pooled Phase 3 Analysis by Race/Ethnicity
July 2020 | Volume 19 | Issue 7 | Original Article | 727 | Copyright © July 2020
Background: Acne vulgaris and inflammation-associated sequelae are highly prevalent in black and Hispanic populations. In a phase 2 study, a novel polymeric emulsion formulation of ta...
Read MoreConsensus on Neonatal Through Preadolescent Acne
June 2020 | Volume 19 | Issue 6 | Original Article | 592 | Copyright © June 2020
Background: Acne vulgaris is the most common dermatological disorder. Pediatric acne may be a manifestation of the underlying pathology and can occur in the first weeks, months, or ye...
Read MoreDemographics and Baseline Disease Characteristics of Early Responders to Crisaborole for Atopic Dermatitis
June 2020 | Volume 19 | Issue 6 | Original Article | 619 | Copyright © June 2020
Introduction: Crisaborole ointment, 2%, is a nonsteroidal phosphodiesterase 4 inhibitor for the treatment of mild-to-moderate atopic dermatitis (AD). This post hoc, pooled analysis id...
Read MoreTreatment of Moderate to Severe Acne and Scars With a 650-Microsecond 1064-nm Laser and Isotretinoin
June 2020 | Volume 19 | Issue 6 | Original Article | 646 | Copyright © June 2020
Background: Laser procedures for acne and acne scars have traditionally been postponed for at least 6 to 8 months after the end of systemic isotretinoin therapy. Lower dosages with mo...
Read MoreNew Polymeric Once-Daily Tazarotene 0.045% Lotion Formulation for Moderate-to-Severe Acne: Pooled Phase 3 Pediatric Analysis
June 2020 | Volume 19 | Issue 6 | Original Article | 602 | Copyright © June 2020
Background: Acne vulgaris affects approximately 85% of adolescents. Topical tazarotene is efficacious and safe for acne treatment but irritation limits its use. The objective was to e...
Read MoreA Double-Blind, Comparative Clinical Study of Newly Formulated Retinol Serums vs Tretinoin Cream in Escalating Doses: A Method for Rapid Retinization With Minimized Irritation
June 2020 | Volume 19 | Issue 6 | Original Article | 625 | Copyright © June 2020
Objective: The goal of this 12 week, double-blinded, controlled, clinical study was to compare the efficacy, tolerability, and consumer acceptance of three novel retinol serums to tre...
Read MoreEvaluation of Patient-Reported Outcomes with Etanercept in Moderate to Severe Plaque Psoriasis Patients After Therapy With Apremilast
April 2020 | Volume 19 | Issue 4 | Original Article | 378 | Copyright © April 2020
Background: Patients with moderate-to-severe psoriasis can have symptoms resulting in significant impact on patient-reported outcomes (PROs). The effect of etanercept (ETN) in moderat...
Read MoreNovel Polymeric Lotion Formulation of Once-Daily Tazarotene (0.045%) for Moderate-to-Severe Acne: Pooled Phase 3 Analysis
March 2020 | Volume 19 | Issue 3 | Original Article | 272 | Copyright © March 2020
Background: As current tazarotene formulations indicated for acne (0.1%) can cause irritation, a new tazarotene 0.045% lotion formu-lation was developed using polymeric emulsion techn...
Read MoreLong-Term Benefits of Daily Photo-Protection With a Broad-Spectrum Sunscreen in United States Hispanic Female Population
March 2020 | Volume 19 | Issue 3 | Original Article | 236 | Copyright © March 2020
The skin of color population has been growing significantly in the United states and globally. This requires specific dermatological attention and patient care strategies due to unique physiological c...
Read MoreMelasma’s Impact on Quality of Life
February 2020 | Volume 19 | Issue 2 | Original Article | 184 | Copyright © February 2020
Melasma is a commonly acquired condition that mostly affects women with Fitzpatrick skin types III-VI with prominent brown pigmentation with or without an underlying erythema. Despite multiple treatme...
Read MoreIngenol Mebutate: Expanded Utility
February 2020 | Volume 19 | Issue 2 | Original Article | 156 | Copyright © February 2020
Ingenol mebutate (IM) is a novel drug that was developed for the treatment of actinic keratosis (AK). The drug works by a dual mechanism of action -- a rapid induction of cell death by necrosis along ...
Read MoreCombination Topical Chemotherapy for the Treatment of an Invasive Cutaneous Squamous Cell Carcinoma
February 2020 | Volume 19 | Issue 2 | Case Reports | 202 | Copyright © February 2020
INTRODUCTION: Standard of care for squamous cell carcinoma (SCC) is usually surgical, with either excision or Mohs micrographic surgery. However, surgery may not be ideal for elderly patients with num...
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