Found 471 articles for: "retinoids"
The Phototoxic and Photoallergy Potential of Clindamycin Phosphate 1.2%/ Tretinoin 0.025% Gel for Facial Acne: Results of Two Single-Center, Evaluator-Blinded, Randomized, Vehicle-Controlled Phase 1 Studies in Healthy Volunteers
January 2014 | Volume 13 | Issue 1 | Original Article | 16 | Copyright © January 2014
BACKGROUND: A fixed-dose combination of clindamycin phosphate 1.2% and tretinoin 0.025% gel (VELTIN® (clindamycin phosphate and tretinoin) 1.2%/0.025% Gel [VELTIN]) (clindamycin/tretinoin gel) is cur...
Read MoreBlockade of Melanin Synthesis, Activation and Distribution Pathway by a Nonprescription Natural Regimen Is Equally Effective to a Multiple Prescription-Based Therapeutic Regimen
December 2013 | Volume 12 | Issue 12 | Original Article | 1449 | Copyright © December 2013
BACKGROUND: Disorders characterized by cutaneous hyperpigmentation (HP) are among the most common complaints in dermatologists' offices. These patients are also some of the most difficult to treat si...
Read MoreEvaluating and Treating the Adult Female Patient With Acne
December 2013 | Volume 12 | Issue 12 | Original Article | 1416 | Copyright © December 2013
Acne vulgaris is a common disease of the pilosebacous unit that affects an estimated 40-50 million Americans. Greater than 95% of teenage boys and between 83% and 85% of teenage girls suffer from acne...
Read MoreA Call to Limit Antibiotic Use in Acne
December 2013 | Volume 12 | Issue 12 | Editorials | 1331 | Copyright © December 2013
With increasing urgency, national and international health authorities are calling for physicians to limit antibiotic use. Generally, physicians are familiar with efforts to reduce antibiotic pre...
Read MoreIntroduction to Special Topic Fillers and Injectables
December 2013 | Volume 12 | Issue 12 | Editorials | 1329 | Copyright © December 2013
The Microsponge Delivery System Reduces Facial Oiliness and Shine During Acne Therapy
November 2013 | Volume 12 | Issue 11 | Original Article | 1268 | Copyright © November 2013
Acne therapies that are able to show efficacious treatment of acne lesions as well as to address the issues of oiliness and shine control may be particularly appropriate for the treatment of patients...
Read MoreNovel Nonablative Radio-Frequency Rejuvenation Device Applied to the Neck and Jowls: Clinical Evaluation and 3-Dimensional Image Analysis
November 2013 | Volume 12 | Issue 11 | Original Article | 1215 | Copyright © November 2013
OBJECTIVE: To use 3D photography to evaluate the clinical efficacy of a novel radiofrequency delivery device used to improve the appearance of rhytids and laxity of the face and neck.
STUDY DE...
Read MoreEfficacy of Combination of Glycolic Acid Peeling With Topical Regimen in Treatment of Melasma
October 2013 | Volume 12 | Issue 10 | Original Article | 1149 | Copyright © October 2013
BACKGROUND: Various treatment modalities are available for management of melasma, ranging from topical and oral to chemical peeling, but none is promising alone. Very few studies are available regardi...
Read MoreCurcumin: A Novel Treatment for Skin-Related Disorders
October 2013 | Volume 12 | Issue 10 | Original Article | 1131 | Copyright © October 2013
Curcumin, or diferuloylmethane, is a crystalline compound which gives the East Asian spice turmeric its bright yellow color. The medicinal properties of this spice have been referenced in numerous cou...
Read MoreCombination Use of Ustekinumab With Other Systemic Therapies: A Retrospective Study in a Tertiary Referral Center
October 2013 | Volume 12 | Issue 10 | Original Article | 1098 | Copyright © October 2013
BACKGROUND: Patients with moderate to severe psoriasis may not respond adequately to single systemic agent and may require combination systemic therapy.
OBJECTIVE: To evaluate the prevalence, i...
Read MorePsoriasis Treatments by Payment Type in the US Outpatient Office Setting
October 2013 | Volume 12 | Issue 10 | Original Article | 1095 | Copyright © October 2013
BACKGROUND: Many factors, including patients' methods of payment, may influence psoriasis treatment decisions.
OBJECTIVE: To characterize psoriasis treatments by patients' types of payment in t...
Read MoreThe Efficacy, Safety and Tolerability of Adapalene Versus Benzoyl Peroxide in the Treatment of Mild Acne Vulgaris; A Randomized Trial
September 2013 | Volume 12 | Issue 9 | Original Article | 1033 | Copyright © September 2013
Topical treatments, such as adapalene and benzoyl peroxide (BPO), are popular in mild-to-moderate acne vulgaris. This study aimed to compare the efficacy, safety and tolerability of adapalene and BPO ...
Read MoreDo We Really Need Topical Antibiotics in Our New Treatment Paradigm of Acne Vulgaris? A Novel Question to Consider Based on an Updated Model of Pathogenesis
August 2013 | Volume 12 | Issue 8 | Supplement Individual Articles | 107 | Copyright © August 2013
Effect of Systemic Isotretinoin Therapy on Mucociliary Clearance and Nasal Surface Mucosa in Acne Patients
August 2013 | Volume 12 | Issue 8 | Original Article | 124 | Copyright © August 2013
BACKGROUND: Currently, there are no studies investigating the topical or systemic effects of retinoids on human nasal mucosa. We aimed to investigate the effect of systemic isotretinoin therapy on muc...
Read MoreDronaderone-Induced Phototoxicity
August 2013 | Volume 12 | Issue 8 | Case Reports | 946 | Copyright © August 2013
Phototoxicity is a skin reaction that occurs in patients using photosensitizing drugs in combination with exposure to ultraviolet light. Common photosensitizing pharmacologic agents include antibiotic...
Read MorePatterns of Vitamin D Analog Use for the Treatment of Psoriasis
August 2013 | Volume 12 | Issue 8 | Original Article | 906 | Copyright © August 2013
BACKGROUND: Psoriasis is a chronic disease that significantly impacts patients’ quality of life. It most commonly manifests as localized disease, for which there are various treatment options.
...
Read MoreEfficacy, Tolerability, and Pharmacodynamics of Apremilast in Recalcitrant Plaque Psoriasis: A Phase II Open-Label Study
August 2013 | Volume 12 | Issue 8 | Original Article | 888 | Copyright © August 2013
BACKGROUND: Apremilast, a small molecule specific inhibitor of phosphodiesterase 4, works intracellularly to modulate pro-inflammatory and anti-inflammatory mediators. This phase II, multicenter, open...
Read MoreEffect of Calcipotriene Plus Betamethasone Dipropionate Topical Suspension on the Hypothalamic-Pituitary-Adrenal Axis and Calcium Homeostasis in Subjects With Extensive Psoriasis Vulgaris: An Open, Non-Controlled, 8-week Trial
August 2013 | Volume 12 | Issue 8 | Original Article | 882 | Copyright © August 2013
BACKGROUND: The two-compound topical suspension/gel containing calcipotriene plus betamethasone dipropionate is effective and safe in the treatment of psoriasis on the body and scalp within the genera...
Read MoreComparative Evaluation of Topical Calcipotriol Versus Coal Tar and Salicylic Acid Ointment in Chronic Plaque Psoriasis
August 2013 | Volume 12 | Issue 8 | Original Article | 868 | Copyright © August 2013
BACKGROUND: Calcipotriol is a newer topical treatment option available for plaque psoriasis and coal tar being one of the oldest treatment and still in use.
AIMS: To evaluate and compare the di...
Read MoreComparison of the Efficacy of Biologics Versus Conventional Systemic Therapies in the Treatment of Psoriasis at a Comprehensive Psoriasis Care Center
August 2013 | Volume 12 | Issue 8 | Original Article | 861 | Copyright © August 2013
BACKGROUND: The efficacy of biologic treatment for psoriasis has not been compared to that of conventional systemic therapies and phototherapy outside of clinical trial settings.
DESIGN: Retros...
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