Found 471 articles for: "retinoids"
Open-Label Study to Evaluate the Efficacy of Etanercept Treatment in Subjects With Moderate to Severe Plaque Psoriasis Who Have Failed Therapy With Apremilast
October 2018 | Volume 17 | Issue 10 | Original Article | 1078 | Copyright © October 2018
INTRODUCTION: Response to etanercept therapy in patients who have failed apremilast therapy has not been well characterized. METHODS: In this multicenter, open-label, single-arm, phase 4, estimatio...
Read MoreRapid Onset of Action in Patients With Moderate-to-Severe Plaque Psoriasis With Halobetasol 0.01%/Tazarotene 0.045% Fixed Combination
August 2018 | Volume 17 | Issue 8 | Original Article | 863 | Copyright © August 2018
Background: Psoriasis is a chronic condition often managed with topical therapy. Patients have high expectations about the speed at which ...
Read MoreCombination Ablative Approach to Laser Therapy in Advanced Aging of the Face
July 2018 | Volume 17 | Issue 7 | Case Reports | 796 | Copyright © July 2018
Background and Objective: Misperceptions have persisted regarding scanning full-field erbium laser that have caused it to be overshadowed by fractional ablative resurfacing. This can lead to sub-optim...
Read MoreNovel Topical Cytokinin Improves Coarse Wrinkles and Skin Roughness Without Skin Irritation
July 2018 | Volume 17 | Issue 7 | Original Article | 772 | Copyright © July 2018
Objective: To evaluate the efficacy and tolerance of topical 4HBAP (para-topolin [6-(4-hydroxybenzylamino) purine], a new aromatic cytokinin, in subjects with mild to moderate facial photodamage. Met...
Read MoreTopical Vehicle Formulations in the Treatment of Acne
June 2018 | Volume 17 | Issue 6 | Supplement Individual Articles | 6 | Copyright © June 2018
Topical treatment is the mainstay of acne therapy. The most commonly prescribed topical medications for acne include benzoyl peroxide, clindamycin, and retinoids. Despite their effectiveness in treati...
Read MoreThe Efficacy and Safety of Azelaic Acid 15% Foam in the Treatment of Facial Acne Vulgaris
June 2018 | Volume 17 | Issue 6 | Original Article | 641 | Copyright © June 2018
Background: Azelaic acid demonstrates anti-inflammatory, anti-oxidative, anti-comedogenic, and anti-microbial effects. Azelaic acid 20% cream is currently approved for the treatment of acne vulgaris, ...
Read MoreFrequency of Treatment Switching for Spironolactone Compared to Oral Tetracycline-Class Antibiotics for Women With Acne: A Retrospective Cohort Study 2010-2016
June 2018 | Volume 17 | Issue 6 | Original Article | 632 | Copyright © June 2018
BACKGROUND: Long-term oral antibiotic use in acne may be associated with a variety of adverse effects including antibiotic resistance, pharyngitis, inflammatory bowel disease, and breast and colon can...
Read MoreWidespread Skin Necrosis Secondary to Gemcitabine Therapy
May 2018 | Volume 17 | Issue 5 | Case Reports | 582 | Copyright © May 2018
Gemcitabine, a pyrimidine nucleoside analogue, is an oncologic agent used in the treatment of cutaneous T-cell lymphoma (CTCL). Common dermatologic reactions associated with gemcitabine include alopec...
Read MoreChlorine Dioxide Complex Cleanser: A New Agent With Rapid Efficacy for Keratosis Pilaris
May 2018 | Volume 17 | Issue 5 | Original Article | 554 | Copyright © May 2018
Chlorine dioxide complex™ is a new molecule to dermatology that is a unique, non-toxic, broad spectrum anti-microbial and keratolytic compound. Chlorine dioxide has been used as an antiseptic in...
Read MoreMulti-Center, Double-Blind, Vehicle-Controlled Clinical Trial of an Alpha and Beta Defensin-Containing Anti-Aging Skin Care Regimen With Clinical, Histopathologic, Immunohistochemical, Photographic, and Ultrasound Evaluation
April 2018 | Volume 17 | Issue 4 | Original Article | 426 | Copyright © April 2018
Background/Objectives: Anti-aging strategies utilizing stem cells are in the forefront. Alpha and beta defensins are natural immune peptides that have been shown to activate an LGR6-positive stem cell...
Read MoreDermal Microflora Restoration With Ammonia-Oxidizing Bacteria Nitrosomonas Eutropha in the Treatment of Keratosis Pilaris: A Randomized Clinical Trial
March 2018 | Volume 17 | Issue 3 | Original Article | 285 | Copyright © March 2018
Keratosis pilaris (KP) is a common skin finding that presents as follicular hyperkeratotic papules on the proximal extremities in patients with a propensity for atopy. Although often asymptomatic, the...
Read MoreEfficacy and Safety of Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel Plus Oral Doxycycline in Subjects With Severe Inflammatory Acne Who Are Candidates for Oral Isotretinoin
March 2018 | Volume 17 | Issue 3 | Original Article | 264 | Copyright © March 2018
INTRODUCTION: Acne treatment guidelines suggest a combination approach with topical therapy including a topical retinoid, benzoyl peroxide and an oral antibiotic, or oral isotretinoin (OI), as first-l...
Read MoreDouble Blind, Placebo Controlled Evaluation of a Novel Skin Lightening Agent
January 2018 | Volume 17 | Issue 1 | Original Article | 113 | Copyright © January 2018
Melasma remains a troubling problem for physicans and patients alike. It is a chronic irregular, symmetric hyperpigmentation seen most often in women. In this study, a unique combination of ingredient...
Read MoreTreatment of Décolletage Photoaging With Fractional Microneedling Radiofrequency
January 2018 | Volume 17 | Issue 1 | Original Article | 74 | Copyright © January 2018
OBJECTIVES: The objective of this study was to examine the efficacy and safety of a novel fractional microneedling radiofrequency device to improve the appearance of rhytides and skin laxity of the dÃ...
Read MoreSafety and Efficacy of a 1550nm/1927nm Dual Wavelength Laser for the Treatment of Photodamaged Skin
January 2018 | Volume 17 | Issue 1 | Original Article | 41 | Copyright © January 2018
BACKGROUND: Fractional photothermolysis (FP) is a popular treatment option for photodamaged skin and addresses shortcomings of ablative skin resurfacing and nonablative dermal remodeling. Previous ...
Read MoreCombining Topical Psoriasis Treatment to Enhance Systemic and Phototherapy: A Review of the Literature
December 2017 | Volume 16 | Issue 12 | Original Article | 1209 | Copyright © December 2017
Psoriasis is a chronic inflammatory skin disease that affects millions of people in the United States as well as worldwide. While there is currently no cure for psoriasis, many treatment options ar...
Read MoreUpregulation of Extracellular Matrix Genes Corroborates Clinical Efcacy of Human Fibroblast-Derived Growth Factors in Skin Rejuvenation
December 2017 | Volume 16 | Issue 12 | Original Article | 1190 | Copyright © December 2017
Skin care products may use various active ingredients to support skin rejuvenation including growth factors and other molecules that help to regenerate extracellular matrix (ECM) and promote skin r...
Read MoreNew Insight Into the Pathophysiology of Hair Loss Trigger a Paradigm Shift in the Treatment Approach
November 2017 | Volume 16 | Issue 11 | Supplement Individual Articles | 135 | Copyright © November 2017
Hair loss affects millions of men and women of all ages and ethnicities, impacting appearance, social interactions, and psycho-emotional well-being. Although a number of options are available, they...
Read MoreA Randomized, Investigator-Blinded Comparison of Two Topical Regimens in Fitzpatrick Skin Types III-VI With Moderate to Severe Facial Hyperpigmentation
November 2017 | Volume 16 | Issue 11 | Original Article | 1127 | Copyright © November 2017
Purpose: Though hydroquinone (HQ) remains the gold standard for treatment of hyperpigmentation, concerns about its safety have prompted the development of HQ-free topical skin lightening systems. ...
Read MoreLasers, Light, and the Treatment of Acne: A Comprehensive Review of the Literature
November 2017 | Volume 16 | Issue 11 | Original Article | 1095 | Copyright © November 2017
Introduction: Acne vulgaris is common dermatologic condition with an estimated prevalence of 70 to 87%. Acne has been shown to have a significant impact on patient quality of life and mental health, e...
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