Found 87 articles for: "petrolatum"
ARTICLE: Compromised Skin Barrier and Sensitive Skin in Diverse Populations
April 2021 | Volume 20 | Issue 4 | Supplement Individual Articles | s17 | Copyright © April 2021
The most important function of the stratum corneum (SC), the uppermost layer of the human epidermis, is the formation of the epidermal permeability barrier. Lipids, particularly ceramides, cholesterol...
Read MoreA Phase 3, Randomized Trial Demonstrating the Improved Efficacy and Patient Acceptability of Fixed Dose Calcipotriene and Betamethasone Dipropionate Cream
April 2021 | Volume 20 | Issue 4 | Original Article | 420 | Copyright © April 2021
Background: The fixed dose combination of calcipotriene and betamethasone dipropionate (CAL/BDP) is a well-established, efficacious, and safe topical treatment of psoriasis.
Read More Wound Healing Treatments After Ablative Laser Skin Resurfacing: A Review
November 2020 | Volume 19 | Issue 11 | Original Article | 1050 | Copyright © November 2020
Laser resurfacing has progressed since the 1980s to treat a variety of medical and aesthetic indications with ever-evolving safety parameters. While laser technology has evolved to provide a more favo...
Read MoreChoosing the Right Partner: Complementing Prescription Acne Medication With Over-the-Counter Cleansers and Moisturizers
November 2020 | Volume 19 | Issue 11 | Original Article | 1069 | Copyright © November 2020
Background: Acne is the most common dermatological disorder. An impaired barrier function in acne vulgaris has been reported, as well as decreased amounts of epidermal ceramides. Also...
Read MoreRed Deer Umbilical Cord-Derived Stem Cell Conditioned Media Combined With Ablative Resurfacing of the Face
November 2020 | Volume 19 | Issue 11 | Original Article | 1044 | Copyright © November 2020
Background: Laser resurfacing is the gold standard procedure for photodamage, but is not without downtime and risk. Use of periprocedural products containing stem cell conditioned med...
Read MoreCutaneous Langerhans Cell Histiocytosis Responsive to Topical Nitrogen Mustard
August 2020 | Volume 19 | Issue 8 | Case Reports | 803 | Copyright © August 2020
Langerhans cell histiocytosis (LCH) limited to the skin is rare in adult patients. Given the challenges of prospective clinical trials for this rare disease, there is paucity in data to guide the mana...
Read MoreSafety and Efficacy of Clobetasol Propionate 0.05% Emollient Foam for the Treatment of Central Centrifugal Cicatricial Alopecia
July 2020 | Volume 19 | Issue 7 | Original Article | 719 | Copyright © July 2020
Background: There is currently an unmet need for the treatment of women with central centrifugal cicatricial alopecia (CCCA).
Objective: To evaluate the safety ...
Read MoreDevelopment of a Photonumeric Lip Health Scale
June 2020 | Volume 19 | Issue 6 | Original Article | 632 | Copyright © June 2020
Background: The lips are important facial anatomic features with particular vulnerability to environmental damage, yet they have received little attention in the dermatologic literatu...
Read MoreThe Effect of a Ceramide-Containing Product on Stratum Corneum Lipid Levels in Dry Legs
April 2020 | Volume 19 | Issue 4 | Original Article | 372 | Copyright © April 2020
Roughly equimolar concentrations of ceramides, cholesterol, and free fatty acids arranged in lamellar sheets form the intercellular lipid barrier in the stratum corneum (SC). Intercellular lipid defic...
Read MoreThe Low Prevalence of Allergic Contact Dermatitis Using a Petrolatum Ointment Containing Lanolin Alcohol
October 2019 | Volume 18 | Issue 10 | Original Article | 1002 | Copyright © October 2019
Lanolin alcohol is a high cholesterol containing naturally derived material used as a skin protectant in wound healing petrolatum-based ointments. It is a highly purified fraction of lanolin wool wax ...
Read MoreIntralesional Steroids for the Management of Periorificial Granulomatous Dermatitis
September 2019 | Volume 18 | Issue 9 | Features | 955 | Copyright © September 2019
A42-year-old male with skin type I and a history of rosacea and eczema presented with crusting, erythema, and pustules distributed on the left oral commissure. Angular cheilitis was diagnosed and regu...
Read MoreA Review of Topical Corticosteroid Foams
August 2019 | Volume 18 | Issue 8 | Original Article | 756 | Copyright © August 2019
Background: Topical corticosteroids are efficacious treatment options for multiple dermatoses. However, ointments and cream corticosteroid vehicles can be cumbersome to patients and m...
Read MoreArterial Occlusion and Necrosis Following Hyaluronic Acid Injection and a Review of the Literature
June 2019 | Volume 18 | Issue 6 | Original Article | 587 | Copyright © June 2019
With the rising popularity of fillers for facial rejuvenation coupled with the paucity of regulations on credentialing of qualified injectors, the number of filler related complications is increasing....
Read MoreTopical Treatment for the Management of Atopic Dermatitis
February 2019 | Volume 18 | Issue 2 | Supplement Individual Articles | 112 | Copyright © February 2019
Atopic dermatitis affects up to 20% of children and continues to increase in prevalence. Effective disease control is aimed at decreasing symptoms and reducing the frequency of flares, which may be co...
Read MoreThe Clinical Relevance and Therapeutic Benefit of Established Active Ingredients Incorporated into Advanced Foam Vehicles: Vehicle Characteristics Can Influence and Improve Patient Outcomes
February 2019 | Volume 18 | Issue 2 | Supplement Individual Articles | 100 | Copyright © February 2019
Topical delivery of therapeutic agents for skin diseases is a major advantage in dermatology. However, the efficacy and tolerability of topically applied therapies is dependent on several characterist...
Read MoreApplications of Topical Oak Bark Extract in Dermatology: Clinical Examples and Discussion
February 2019 | Volume 18 | Issue 2 | Original Article | 203 | Copyright © February 2019
The versatility of wound healing and anti-inflammatory agents can be assets to dermatologists when other therapies lack appropriate mechanisms of action, or when the risk to benefit ratio may be in qu...
Read MorePrinciples of Moisturizer Product Design
January 2019 | Volume 18 | Issue 1 | Supplement Individual Articles | 89 | Copyright © January 2019
Moisturizers provide significant benefit in dermatology – as adjuvant therapy for many clinical conditions, as a key player in anti-aging regimens, and as a core component in maintaining healthy ski...
Read MoreRecent Advances in Mild and Moisturizing Cleansers
January 2019 | Volume 18 | Issue 1 | Supplement Individual Articles | 80 | Copyright © January 2019
Mild and moisturizing cleanser technologies, and the science underpinning them, have progressed significantly over the past decade. This includes introduction of amino-acid based milder surfactants in...
Read MoreTazarotene Revisited: Safety and Efficacy in Plaque Psoriasis and Its Emerging Role in Treatment Strategy
December 2018 | Volume 17 | Issue 12 | Original Article | 1280 | Copyright © December 2018
BACKGROUND: Psoriasis is a chronic, immune-mediated disease that varies widely in its clinical expression. Treatment options focus on relieving symptoms, reducing inflammation, induration, and scaling...
Read MoreA Natural Cream-to-Powder Formulation Developed for the Prevention of Diaper Dermatitis in Diaper-Wearing Infants and Children: Barrier Property and In-Use Tolerance Studies
May 2018 | Volume 17 | Issue 5 | Original Article | 566 | Copyright © May 2018
Introduction: Diaper dermatitis is a common condition that develops in the diaper area due to factors such as elevated moisture, increased skin surface pH, and exposure to irritants from urine and fec...
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