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Treating Acne Vulgaris and Scarring With Botulinum Toxin: A Systematic Review

By June 5, 2026No Comments

JDD Review: Botulinum Toxin A Shows Potential for Acne Vulgaris and Acne Scarring

You don’t want to miss this article in the JDD. A systematic review in the Journal of Drugs in Dermatology compiles available evidence on botulinum toxin A as a treatment for acne vulgaris and acne scarring, offering a concise resource for practicing dermatologists and dermatology healthcare professionals interested in novel therapeutic options.

The authors searched multiple databases and identified 14 manuscripts encompassing 436 patients, evenly split between acne vulgaris and acne scarring cohorts. Reported outcomes included reductions in sebum production measured by sebometer, improvements in fine pore counts, decreases in lesion counts, and high patient satisfaction. Many patients experienced benefit for up to three to six months. Acne scar appearance reportedly improved when botulinum toxin A was used alone and when combined with other interventions. Safety and efficacy data are summarized across the included studies.

For clinicians evaluating treatment options, this review presents aggregated data on efficacy measures, duration of effect, and patient reported outcomes, while noting the scope of the existing literature. Details on study design, dosing, administration techniques, and adverse events are essential to interpret applicability in practice and are available in the full paper.

If you treat patients with refractory acne or are exploring adjunctive strategies for acne scarring, consult the full JDD review to examine methodology, specific outcome metrics, and considerations for integrating botulinum toxin A into clinical protocols. The article may help inform discussions with patients about expected benefits, treatment intervals, and evidence gaps that require further study.

Blog write-up assisted by AI