Found 12 articles for: "keloid"
Cardamonin Inhibits Keloid Fibroblast Activation and Extracellular Matrix Production Through Suppression of TGF-β1/Smad Signaling
September 2026 | Volume 25 | Issue 9 | Original Article | 857 | Copyright © September 2026
Background: Keloids are pathological scars characterized by persistent fibroblast activation and excessive extracellular matrix (ECM) deposition. Cardamonin (CARD), a natural cha...
Read MoreJAK/STAT Inhibitors Reduce Risk of New-Onset Keloids and Hypertrophic Scars: A Multi-Center Retrospective Cohort Study
September 2026 | Volume 25 | Issue 9 | Original Article | 779 | Copyright © September 2026
Background: Keloids and hypertrophic scars are fibroproliferative skin disorders characterized by excessive collagen deposition and high recurrence rates despite existing therapi...
Read MoreDifferences in Keloid and Hypertrophic Scar Treatment Patterns by Race
September 2026 | Volume 25 | Issue 9 | Editorials | e81 | Copyright © September 2026
Analysis of Therapeutic Interventions for Hypertrophic and Keloid Scarring: A Systematic Review
August 2025 | Volume 24 | Issue 8 | Original Article | 770 | Copyright © August 2025
This systematic review compares the efficacy of pressure garment therapy (PGT) and non-PGT treatments, such as triamcinolone, verapamil, and laser therapies, for hypertrophic and keloid scars. Fo...
Read MoreInsights Into Demographics, Comorbidities, and Risk Factors in Keloids and Hypertrophic Scars: A Retrospective Study
February 2025 | Volume 24 | Issue 2 | Features | 212 | Copyright © February 2025
Hypertrophic scars and keloids represent abnormal wound healing, manifesting as raised scars confined to or extending beyond the wound margin, respectively. Understanding the risk factors associated w...
Read MoreKeloidal Morphea: A Unique Variant of Morphea Presenting in a Black Female
February 2025 | Volume 24 | Issue 2 | Case Reports | 203 | Copyright © February 2025
Keloidal morphea is a rare variant of cutaneous scleroderma that presents with keloid-like plaques and nodules that occur most commonly on the neck, trunk, and proximal extremities. They occur in...
Read MoreA Review of Energy-Based Device Interventions to Treat Keloid Scars
November 2024 | Volume 23 | Issue 11 | Original Article | 998 | Copyright © November 2024
Keloids are thickened raised scars that develop due to injury and grow beyond the boundaries of their original wound, mostly affecting individuals with skin of color. This review explores the use...
Read MoreRepresentation of Skin of Color in Social Media Discussions on Melasma, Keloids, and Vitiligo
July 2024 | Volume 23 | Issue 7 | Original Article | 510 | Copyright © July 2024
Background: The prevalence of social media as a source of medical information has grown substantially in recent years, especially for skin conditions disproportionately affecting...
Read MoreSuccessful Treatment of Keloids and Hypertrophic Scars With Systemic and Intralesional Dupilumab
December 2023 | Volume 22 | Issue 12 | Case Reports | 1220 | Copyright © December 2023
Keloids and hypertrophic scars negatively impact the quality of life for millions of people in the world. Unfortunately, though many thera-peutic approaches are used to treat scars, they are ofte...
Read MoreOnline Health Information for Acne Keloidalis Nuchae has a Difficult Level of Readability
February 2023 | Volume 22 | Issue 2 | Original Article | 195 | Copyright © February 2023
Background: Acne keloidalis nuchae (AKN) is an inflammatory disorder primarily seen in individuals of color, characterized by acneiform and keloidal lesions on the occipital scalp/nuc...
Read MoreNonresponse and Progression of Diffuse Keloids to Dupilumab Therapy
February 2022 | Volume 21 | Issue 2 | Case Reports | 197 | Copyright © February 2022
Th2 cytokines, including IL-4 and IL-13, have been shown to increase TGFβ, promoting fibrosis. A recent study showed keloid improvement in one patient after administration of Dupilumab, an IL-4 r...
Read MoreA Randomized, Double-Blind, Active- and Placebo-Controlled Trial Evaluating a Novel Topical Treatment for Keloid Scars
September 2021 | Volume 20 | Issue 9 | Original Article | 964 | Copyright © September 2021
Keloid and hypertrophic scars are fibroproliferative disorders resulting from abnormal wound healing in genetically susceptible individuals. Current therapies are often ineffective. Kynurenine shows p...
Read More© 2026 Journal of Drugs in Dermatology. All Rights Reserved. JDD, a peer-reviewed, MEDLINE®/PubMed® indexed journal, offers the dermatology community strong content of utmost quality and relevance on drugs, devices, and methods.
