Found 27 articles for: "clinical"
Evaluating the Clinical Efficacy, Utility, and Role of the 40-Gene Expression Profiling Test in Assessing Prognosis of Cutaneous Squamous Cell Carcinoma: An Expert Consensus Panel
November 2026 | Volume 25 | Issue 11 | Original Article | 1051 | Copyright © November 2026
Background: The 40-gene expression profiling (40-GEP) test has been validated to identify patients at highest risk for nodal or distant metastasis, as well as those most likely t...
Read MoreBruton Tyrosine Kinase Inhibitors for Systemic Lupus Erythematosus: A Systematic Review of Randomized Controlled Trials
November 2026 | Volume 25 | Issue 11 | Original Article | 1039 | Copyright © November 2026
Background: Systemic lupus erythematosus (SLE) is a chronic relapsing autoimmune disease with frequent cutaneous involvement and unmet treatment need. Given safety and efficacy c...
Read MoreRacial and Ethnic Representation in Clinical Trials of Janus Kinase Inhibitors for Dermatologic Conditions: A Systematic Review
April 2026 | Volume 25 | Issue 4 | Original Article | 316 | Copyright © April 2026
Background: Janus kinase (JAK) inhibitors represent promising therapies for dermatologic conditions, including psoriasis, hidradenitis suppurativa (HS), atopic dermatitis (AD), s...
Read MoreObjective Measures Needed: Dermatology Program Directors' Perspectives on the USMLE Step 1 Pass/Fail Transition
April 2026 | Volume 25 | Issue 4 | Original Article | 345 | Copyright © April 2026
Background: Since January 2022, the United States Medical Licensing Examination (USMLE) Step 1 discontinued reporting a 3-digit score. The objective of this study is to share sur...
Read MoreThe Current Landscape of Treatment of Warts
December 2025 | Volume 24 | Issue 12 | Original Article | 1208 | Copyright © December 2025
Warts have bothered people since the early Greek and Roman empires.5 For centuries, people have studied causes of and treatments for these irritating tumors. In recent history, treatme...
Read MoreDisparities in Hidradentitis Suppurativa Clinical Trials: An Updated Review of ClinicalTrials.gov from 2020 to 2024
December 2025 | Volume 24 | Issue 12 | Original Article | 1203 | Copyright © December 2025
Background: There is a notable lack of diversity in dermatologic studies, even concerning conditions that are known to have a higher prevalence in the skin of color (SOC) populat...
Read MoreConnecting the Plaques: Exploring the Link Between Dupilumab and Cutaneous T-cell Lymphoma
November 2025 | Volume 24 | Issue 11 | Features | 1148 | Copyright © November 2025
The Current Landscape of Vitiligo Treatment Centers
August 2025 | Volume 24 | Issue 8 | Editorials | e51 | Copyright © August 2025
Novel 2% Salicylic Acid Cleanser With Polymeric Cleansing Technology Treats Acne Without Compromising Skin Barrier
June 2025 | Volume 24 | Issue 6 | Original Article | 570 | Copyright © June 2025
Background: A novel acne cleanser containing 2% Salicylic acid (SA), Polymeric Cleansing Technology (PCT), and a microgel complex, was evaluated for its efficacy in treating mild...
Read MoreTreatment of Acne-Induced Macular Hyperpigmentation in Fitzpatrick Skin Types V - VI: A Scoping Review
June 2025 | Volume 24 | Issue 6 | Original Article | 579 | Copyright © June 2025
Acne-induced macular hyperpigmentation (AMH) is a common issue among patients with highly melanated skin, particularly those with Fitzpatrick Skin Types (FST) V - VI, which includes nonwhite pati...
Read MoreClinical Utility of TRPV1 Modulation for Skincare Sensitivity
April 2025 | Volume 24 | Issue 4 | Original Article | 366 | Copyright © April 2025
The Transient Receptor Potential Vanilloid 1 (TRPV1) protein, originally recognized for its role in modulating peripheral sensory neurons and transmitting pain and itch signals, has been increasi...
Read MoreRituximab in the Treatment of Epidermolysis Bullosa Acquisita: A Systematic Review of the Literature
April 2025 | Volume 24 | Issue 4 | Original Article | 387 | Copyright © April 2025
Read MoreRacial and Ethnic Representation in Atopic Dermatitis Clinical Trials
April 2025 | Volume 24 | Issue 4 | Original Article | 360 | Copyright © April 2025
Read MoreDupilumab Treatment Improves Lichenification in Atopic Dermatitis in Different Age and Racial Groups
February 2025 | Volume 24 | Issue 2 | Original Article | 167 | Copyright © February 2025
Background: Lichenification, common in moderate to severe atopic dermatitis (AD) at any age, is often difficult to treat. This analysis assessed dupilumab vs placebo in AD lichen...
Read MoreNon-Surgical Correction of Dermatochalasis Using Microplasma
February 2025 | Volume 24 | Issue 2 | Original Article | 134 | Copyright © February 2025
Background: Dermatochalasis is characterized by the presence of redundant and loose upper eyelid skin, which occurs as part of the aging process and is often considered aest...
Read MoreUse of Upadacitinib in Refractory Behcet's Disease: Case Report and Systematic Literature Review
February 2025 | Volume 24 | Issue 2 | Case Reports | e1 | Copyright © February 2025
IL-36 Trials in Dermatology: Cross-Sectional Analysis of ClinicalTrials.gov-Registered Trials
December 2024 | Volume 23 | Issue 12 | Editorials | e195 | Copyright © December 2024
Isobutylamido Thiazolyl Resorcinol (Thiamidol) for Combatting Hyperpigmentation: A Systematic Review of Clinical Studies
November 2024 | Volume 23 | Issue 11 | Original Article | 986 | Copyright © November 2024
Background: Tyrosinase is the rate-limiting enzyme of melanogenesis and thus an ideal inhibitory target for treating hyperpigmentation. There are many commercially available tyro...
Read MoreExtension Phase of a Multi-Center, Randomized, Blinded Clinical Study Evaluating the Efficacy and Safety of a Novel Topical Product for Facial Dyschromia
January 2024 | Volume 23 | Issue 1 | Original Article | 1266 | Copyright © January 2024
Background: Dyschromia can be associated with increased production and/or reduced clearance of pigmentation in the skin. Multiple pathways are involved in causality. A novel topi...
Read MoreSkin of Color Representation in Clinical Trials: An Analysis of Clinicaltrials.gov From 2008-2022
March 2023 | Volume 22 | Issue 3 | Features | 310 | Copyright © March 2023
There is a plethora of dermatologic clinical trials; however, little is known regarding the representation of skin of color (SOC) populations. We evaluated the 15 most prevalent skin conditions in SOC...
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