JDD Special Focus

Skin Cancer

Stay up-to-date on new clinical findings in Skin Cancer  View the latest articles, case reports, supplements, podcast episodes and more!



Basal Cell Carcinoma Gene Mutations Differ Between Asian, Hispanic, and Caucasian Patients: A Pilot Study

Do gene mutations in basal cell carcinoma vary between Hispanic, Asian and Caucasian patients? How do gene mutations in skin of color inform therapy options and course of treatment?

The Potential Efficacy of β-Blockers on Melanoma Survival: A Narrative Review

What is the role of role and status of β-blockers in melanoma management?

A Review of Hedgehog Inhibitors Sonidegib and Vismodegib for Treatment of Advanced Basal Cell Carcinoma

Compare systemic Hedgehog inhibitors (HHIs) sonidegib and vismodegib for efficacy, safety, and pharmacokinetics. [FREE TEXT]

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Case Reports

Basal Cell Carcinoma in the Nasal Vestibule

Basal cell carcinomas (BCC) arise from DNA damage to cells of the basal layer of the epidermis and most commonly in areas of the skin exposed to sunlight or ultraviolet radiation. BCC is the most common skin cancer seen in humans with over 4.3 million cases reported in the United States and is responsible for 3-10% of all cancers annually. We report what we believe to be the first case of this very prevalent skin cancer arising in the nasal vestibule. The lesion was treated with Mohs micrographic surgery and required three stages to obtain histological clearance. Given the location of the tumor, Mohs surgery was chosen due to the procedure’s effectiveness for achieving the highest cure rate with the lowest incidence of tumor recurrence and for preserving as much adjacent healthy tissue as possible

Combination Topical Chemotherapy for the Treatment of an Invasive Cutaneous Squamous Cell Carcinoma

Standard of care for squamous cell carcinoma (SCC) is usually surgical, with either excision or Mohs micrographic surgery. However, surgery may not be ideal for elderly patients with numerous lesions, who are poor surgical candidates or who refuse surgery. Topical 5-fluorouracil (5-FU) and imiquimod have been studied off-label as monotherapies in the treatment of SCC in situ with promising results. However, long-term tumor-free survival rates are still less than with surgical management.

Recurrent Squamous Cell Carcinoma Arising Within a Linear Porokeratosis

Here we report a case of linear porokeratosis with recurrent malignant degeneration to squamous cell carcinoma (SCC) recurring six years after excision of initial SCC. A 79-year-old woman presented with a friable tumor located within a longstanding lesion on her posterior thigh. Six years prior, she was diagnosed with SCC arising within the same lesion, which had been surgically excised with negative margins. Physical examination revealed a 3.5 x 2.7 cm friable tumor on the left proximal posterior thigh.

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Podcast Episodes

Support the (On)cause: A Practical Review of Supportive Oncodermatology

Dr. Mario Lacatoure joins podcast host Dr. Adam Friedman to discuss the array of cutaneous clusters that not only can, but are almost expected to occur during cancer therapy. Learn how even simple OTC products can contribute to both ameliorating and even preventing some of these sequelae.

Identifying Gaps in Sun Protection Perceptions and Use in Native Americans

Skin cancer doesn’t discriminate. We hear that evidenced-based media-friendly line often nowadays to highlight the importance of sun protection in all skin types. But are we really getting that message everywhere it needs to be? Definitely not. Dr. Vivian Shi’s most recent study published in the June 2019 edition of JDD highlights clear shortcomings in the Native American communities in Arizona. Tune in to hear how this study came to light, what unique concerns and issues impede proper sun protection in this group, and tricks to get even a nonbeliever on a photoprotective regimen that he or she can realistically stay on.

Variations in Skin Cancer Screening Practices Among Dermatologist

Dr. Adam Friedman and Dr. Evan Rieder, Assistant Professor of Dermatology at NYU Langone Medical Center and one of the few dermatologists double board certified in dermatology and psychiatry in the U.S., to discuss his recent study entitled “Dermatologist Practices During Total Body Skin Examinations: A Survey Study.” Do we all do it the same? Are we all checking every nook and cranny? Do we need better standardization for our greatest weapon to enable early and life saving skin cancer detection?



Skin Cancer in Hispanics in the United States

The American Cancer Society reported that Cancer remains leading cause of death in Hispanics. Lung cancer for men and breast for women. Non-melanoma skin cancer (NMSC) is the most common malignancy in the United States, over 3.5 million in over 2 million people, incidence rising at about 2.6% per year.

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Dermatology News

Neutrogena Face Sunscreen Suncare for AllJDD HighlightsJDD Webinars
May 10, 2021

Suncare for All: New Insights and Solutions for Protecting Patients of All Skin Tones

Supported By   Watch an important discussion with thought leaders in dermatology, behavioral science and sunscreen innovation, including new original research on multicultural beliefs and challenges in photoprotection. Faculty Shirley…
Derm CommunityFeatured ArticlesJDD Highlights
May 3, 2021


SanovaWorks has developed a partnership with and in support of Comprehensive Medical Mentoring Program. We are happy to announce that SanovaWorks will match the CMMP Medical Student Grant fund, which was…
Dyshidrotic eczema picture on the sole of the footFeatured ArticlesJDD Highlights
April 26, 2021

New Treatment for Dyshidrotic Eczema

Struggling with how to treat dyshidrotic eczema of the hands, palms, fingers or feet? We explore the use of a new medication in the treatment of dyshidrotic eczema and common…
CME ActivitiesJDD Webinars
April 15, 2021

Actinic Keratosis: Therapeutic Options and Evolving Considerations

Watch Now to Earn 1.0 CE Credit!  Join JDD for Part Two of this two-part webinar series on "Advancing the Understanding of Actinic Keratosis: New Treatment Options and Strategies." In…