Found 34 articles for: "cortisol"
Update on the Systemic Risks of Superpotent Topical Steroids
July 2017 | Volume 16 | Issue 7 | Original Article | 643 | Copyright © July 2017
INTRODUCTION: The potential for systemic effects due to percutaneous absorption of superpotent topical steroids has been a longstanding concern. The Food and Drug Administration currently recommend...
Read MoreA Randomized Controlled Study of a Novel Botanical Acne Spot Treatment
June 2017 | Volume 16 | Issue 6 | Original Article | 599 | Copyright © June 2017
OBJECTIVE: The study evaluated the tolerability and efficacy of a new presented treatment for acne. The product is an OTC topical gel consisting of 2% SA, which is also enriched in botanicals that ...
Read MoreTransitioning From Brand to Generic With Topical Products and the Importance of Maintaining the Formulation and Therapeutic Profiles of the Original Product: Focus on Clocortolone Pivalate 0.1% Cream
July 2014 | Volume 13 | Issue 7 | Supplement Individual Articles | 77 | Copyright © July 2014
Topical corticosteroids (TCSs) are a major part of the foundation of treatment for a wide variety of eczematous and inflammatory skin disorders in both adults and children. Mid-potency TCSs represent ...
Read MoreClinical Study Results of Desoximetasone Spray, 0.25% in Moderate to Severe Plaque Psoriasis
December 2013 | Volume 12 | Issue 12 | Original Article | 1404 | Copyright © December 2013
Two Phase 3, double-blind, randomized, vehicle-controlled parallel studies evaluated the efficacy and safety of desoximetasone spray 0.25%, a super-potent topical corticosteroid, twice daily vs vehicl...
Read MoreEffect of Calcipotriene Plus Betamethasone Dipropionate Topical Suspension on the Hypothalamic-Pituitary-Adrenal Axis and Calcium Homeostasis in Subjects With Extensive Psoriasis Vulgaris: An Open, Non-Controlled, 8-week Trial
August 2013 | Volume 12 | Issue 8 | Original Article | 882 | Copyright © August 2013
BACKGROUND: The two-compound topical suspension/gel containing calcipotriene plus betamethasone dipropionate is effective and safe in the treatment of psoriasis on the body and scalp within the genera...
Read MoreTreating Seborrheic Dermatitis: Review of Mechanisms and Therapeutic Options
July 2013 | Volume 12 | Issue 7 | Original Article | 796 | Copyright © July 2013
Seborrheic dermatitis is one of those conditions that dermatologists and patients alike tend to find a routine for, and in many cases those routines are hard to break. And, unlike the new treatment pa...
Read MoreA Multicenter, Randomized, Double-Blind Study of the Efficacy and Safety of Calcipotriene Foam, 0.005%, vs Vehicle Foam in the Treatment of Plaque-type Psoriasis of the Scalp
March 2013 | Volume 12 | Issue 3 | Original Article | 300 | Copyright © March 2013
BACKGROUND: Calcipotriene ointment and cream are effective treatments for psoriasis, but many patients with scalp psoriasis prefer lighter, less messy vehicles.
OBJECTIVES: To evaluate the effic...
Read MoreThe Role of a Midpotency Topical Corticosteroid and the Clinical Relevance of Formulation Characteristics in the Management of Commonly Encountered Eczematous and Inflammatory Dermatoses in Adults and Children:Focus on the Pharmacologic Properties of Clocortolone Pivalate 0.1% Cream
February 2013 | Volume 12 | Issue 2 | Supplement Individual Articles | 5 | Copyright © February 2013
Midpotency topical corticosteroids (TCSs) are frequently used for the treatment of common eczematous and inflammatory skin disorders in both adults and children. There are several commercially availab...
Read MoreInhaled Corticosteroid-Induced Hair Depigmentation in a Child
January 2013 | Volume 12 | Issue 1 | Case Reports | 119 | Copyright © January 2013
An Afro-Caribbean girl showed localized hair depigmentation during treatment with inhaled fluticasone propionate. Although skin depigmentation is common after topical use of corticosteroids, hair depi...
Read MoreRegional Variations in Percutaneous Absorption
October 2012 | Volume 11 | Issue 10 | Original Article | 48 | Copyright © October 2012
Background: In its simplest definition, percutaneous absorption (PA) is the amount of substance that passes through the stratum corneum compared with the amount applied. The study of the PA of ...
Read MoreNews, Views, & Reviews
The Outer Aspect of Our Inner Anxiety: The Skinny on StressJuly 2012 | Volume 11 | Issue 7 | Features | 883 | Copyright © July 2012
Comparative Trial of 5% Dexpanthenol in Water-in-Oil Formulation With 1% Hydrocortisone Ointment in the Treatment of Childhood Atopic Dermatitis: A Pilot Study
March 2012 | Volume 11 | Issue 3 | Original Article | 366 | Copyright © March 2012
Background: Atopic dermatitis (AD) is a common chronic relapsing disease particularly affecting children. The emollient used for protection of skin barrier function is the standard treatment fo...
Read MoreCentral Serous Chorioretinopathy Associated With Topical Corticosteroids in a Patient With Psoriasis
August 2011 | Volume 10 | Issue 8 | Case Reports | 918 | Copyright © August 2011
Background: Central serous chorioretinopathy (CSC), also known as central serous retinopathy (CSR), is a visual impairment, often temporary, ...
Read MoreTamoxifen-Induced Hirsutism
July 2011 | Volume 10 | Issue 7 | Case Reports | 799 | Copyright © July 2011
Tamoxifen, a triphenylethylethylene, is an adjuvant therapy used for the treatment of oestrogen-receptor positive breast carcinoma due to its oestrogen receptor antagonist effect.1 We report here a c...
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