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Issue Archive
October 2023 | Volume 22 | Issue 10
Editorials
Unexpected Clinical Lessons Learned From IL-4 and IL-13 Blockade
In 2017, dupilumab became the first FDA approved systemic therapy for atopic dermatitis. Since its approval, extensive clinical experience and continued research have revealed a number of unexpected e...
Read MoreTopical Ivermectin Is Associated With Improved Erythematotelangiectatic, Papulopustular, and Phymatous Rosacea in a Secondary Analysis
Rosacea has variable clinical presentation consisting of four overlapping phenotypes: erythematotelangiectatic, papulopustular, phymatous, and ocular.1 Rosacea's pathogenesis involves increased cutane...
Read MoreParticipant Satisfaction of a Community-based Telehealth Clinic for Atopic Dermatitis
Atopic dermatitis (AD), a chronic, relapsing inflammatory disease that affects more than 30 million children and adults in the US, disproportionally impacts African American (AA) and Hispanic children...
Read MoreEnsuring Dermatologists Practice Enhanced Antibiotic Stewardship With Sarecycline Mnemonic
It must be ensured that dermatologists practice enhanced antibiotic stewardship to combat antimicrobial resistance and negative consequences of microbiome dysbiosis. In order to help achieve this, we ...
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Original Articles
Keratosis Pilaris: Treatment Practices of Board-Certified Dermatologists
Keratosis pilaris (KP) is a chronic disorder of follicular hyperkeratinization and perifollicular erythema with lesions affecting the extensor surfaces of arms, upper legs, and buttocks. While there i...
Read MoreA Review of the Current Landscape of Hidradenitis Suppurativa Treatment Development
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterized by recurrent nodules and abscesses leading to subsequent scarring and tunnel formation. Despite being a...
Read MorePost-Hoc Exploratory Pooled Analysis of the Impact of IDP-126 Gel on QoL in Moderate-to-Severe Acne
Background: Acne has psychosocial effects on patient's quality of life (QoL). This post hoc exploratory analysis of pooled phase 3 data assessed the impact of investigational IDP-126 gel (for moderate...
Read MoreThe Association Between Herpes Simplex Virus and Alzheimer's Disease: A Systematic Review
Alzheimer's disease (AD) is a significant public health concern, affecting more than 6 million Americans; and currently, there are no cure or effective treatment options. The underlying etiology and p...
Read MoreComparing the Efficacy for Pulse Versus Continuous Dose Terbinafine Therapy in Patients With Onychomycosis
Recently, treatment outcomes in patients with toenail onychomycosis have improved considerably due to more effective oral antifungal medications such as terbinafine and itraconazole. These medications...
Read MoreThe Psychosocial Burden of Skin Disease and Dermatology Care Insights Among Skin of Color Consumers
Background: Skin conditions are associated with psychological symptoms and may be particularly distressing for skin of color (SoC) individuals. SoC consumers' decisions to pursue dermatology care may ...
Read MoreAnt Venom-Based Ceramide Therapy Is Effective Against Atopic Dermatitis In Vivo
Background: Atopic dermatitis (AD) is a common skin condition with relatively few therapeutic alternatives. These include corticosteroids, which address inflammation but not superinfection, and Januse...
Read MoreMechanism of Action of Brodalumab May Correlate With Efficacy in Patients With Inflammatory Skin Diseases
Biologic therapy is used for systemic treatment of multiple inflammatory conditions, including moderate-to-severe plaque psoriasis. Brodalumab is an interleukin-17 (IL-17) receptor A antagonist indica...
Read MoreOnychomycosis Treatment Prescribed at Only Twenty Percent of Visits: A Cross-Sectional Analysis of the National Ambulatory Medical Care Survey 2007 to 2016
Background: Onychomycosis represents the highest proportion of nail disorders seen in clinical practice. Onychomycosis management may differ amongst specialties, with impact on patient outcomes and qu...
Read MoreSelection of Nemolizumab Clinical Dosage for Atopic Dermatitis
Nemolizumab is a monoclonal antibody directed against the interleukin-31 receptor A subunit, which is involved in the pathogenesis of pruritus and inflammation in atopic dermatitis (AD). Clinical tria...
Read MoreCidofovir in the Management of Non-Genital Warts: A Review
Introduction: Cutaneous warts are one of the most frequent reasons for visits to the dermatologist. While there are many treatment options available and commonly used to treat warts, recurrence of les...
Read MoreA Review of the Efficacy of Topical Statins for Treating Disseminated Superficial Actinic Porokeratosis
Porokeratosis is a rare group of acquired or hereditary dermatoses characterized by linear or annular plaques with a keratotic border. DSAP is the most common porokeratosis, and lesions range from asy...
Read MoreAlopecia Areata: The Clinician and Patient Voice
Alopecia areata (AA), an autoimmune disorder of hair follicles, results in varying degrees of scalp, facial, and body hair loss. In addition, it is associated with profound psychosocial and quality-of...
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Features
Updates in the Treatment of Body-Focused Repetitive Disorders
Body-focused repetitive disorders (BFRBs) are psychocutaneous disorders that are underrecognized and undertreated....
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Case Reports
Successful Treatment of Lichen Planus With Oral Upadacitinib
Lichen planus is an auto-inflammatory skin disorder marked by intensely pruritic, violaceous papules that commonly affect the extremities of middle-aged adults.1 There are several treatment options av...
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Departments
FULL SUPPLEMENT: Brodalumab: Five Years of Real-World Safety and Efficiency
Psoriasis remains a highly prevalent condition in the United States and worldwide. Preclinical research has been triumphant in elucidating the critical immunological pathways involved in psoriasis. Th...
Read MoreFULL SUPPLEMENT: The Importance of Skincare in Eczema: A Novel Over-the-Counter Routine Improves Signs and Symptoms in Patients with Eczema
In the United States, the National Eczema Association estimates that 1 out of every 10 people have some form of eczema over their lifetime. As any dermatologist can attest, managing patients with ecze...
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Supplements
Individual Article: Efficacy of Over-The-Counter Cream in Reducing Eczema Signs
Background: Eczema (also called atopic dermatitis) is a chronic, relapsing skin disease characterized by erythema, scaling, and pruritus.
Methods: Study 1. A double-blind, uncontrolled study in ...
Read MoreIndividual Article: Over-the-Counter Moisturizers Significantly Improve Skin Hydration in Adults With Eczema/Atopy-Prone Skin
Background: Many adults suffer from dry, itchy skin, particularly those with eczema-prone skin. This study evaluated the effects of two over-the-counter (OTC) moisturizing products on skin hydration, ...
Read MoreIndividual Article: A Novel 3-Step Over-the-Counter Eczema Regimen Improves Eczema Severity, Itch, and Life Quality: Randomized Study
Background: Eczema, or atopic dermatitis (AD), is a chronic relapsing skin disease associated with unpredictable flares of erythema, rash, and pruritus. AD arises from a combination of immune system d...
Read MoreIndividual Article: Evaluation of Efficacy and Tolerability of Two Over-the-Counter Eczema Itch Relief Products
Background: Study to compare efficacy, tolerability, and patient perception between an over-the-counter itch relief gel (IRG) and itch relief moisturizing cream (IRMC) after a single application. ...
Read MoreIndividual Article: Brodalumab Is an Efficacious, Safe, and Cost-Effective IL-17 Receptor Blocker for the Treatment of Moderate-to-Severe Plaque Psoriasis: 2023 Update
Psoriasis remains a highly prevalent condition in the United States and worldwide. Preclinical research has been triumphant in elucidating the critical immunological pathways involved in psoriasis. Th...
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