Issue Archive
April 2023 | Volume 22 | Issue 4
Original Articles
Do Atopic Dermatitis Patient-Reported Outcomes Correlate With Validated Investigator Global Assessment? Insights From TARGET-AD Registry
Background: Research examining associations between the clinician-reported validated Investigator Global Assessment for AD (vIGA-AD) and patient-reported disease burden is sparse. This study aims to e...
Read MoreOptimizing Melasma Management With Topical Tranexamic Acid: An Expert Consensus
Because of its complex pathogenesis, chronicity, and high rates of recurrence, melasma is regarded as a challenging skin disorder. Topical treatments are often offered as first-line therapy. However, ...
Read MoreAlgorithm to Improve Patient Comfort and Treat Diabetes Mellitus-Related Xerosis
Background: Diabetes mellitus (DM)-related cutaneous disorders such as xerosis frequently occur in patients with type 1 and type 2 diabetes. Gentle cleansers and moisturizers are underused to prevent ...
Read MoreThe Overview of the Immunobiology of Interleukin-23 Associated With Immune-Mediated Inflammatory Disorders: A Narrative Review
Background: Interleukin (IL)-23, a member of the IL-12 family, has emerged as an important cytokine that bridges the innate and adaptive immune systems and plays a critical role in the development of ...
Read MoreDouble-Blind, Placebo-Controlled Study of Onabotulinumtoxin A for the Treatment of Hailey-Hailey Disease
Background: Hailey-Hailey disease (HHD) can be treated with topical steroids, antibiotics, and invasive surgical procedures. Since sweating often exacerbates HHD lesions, the use of onabotulinumtoxin ...
Read MoreA Comparative Analysis of Local Anesthetics: Injection Associated Pain and Duration of Anesthesia
Background: Local anesthesia administration is frequently the most painful step of dermatologic surgery. Identification of an anesthetic that minimizes infiltration pain and toxicity while maximizing ...
Read MoreA Systematic Review: Landscape of Private Equity in Dermatology From Past to Present
The primary objective of this abstract is to define the growing trend of private equity (PE) backed consolidation of dermatology practices and explore its impact on patient care. The secondary objecti...
Read MoreThe Effectiveness of Intralesional Platelet Rich Plasma in Recurrent Aphthous Stomatitis Compared With Triamcinolone Acetonide
Background: Recurrent aphthous stomatitis (RAS) is an autoimmune disease that affects 25% of the population, with no cure until now. Intralesional triamcinolone acetonide (TA) injections are an effect...
Read MoreDrugs in Development for Chronic Spontaneous Urticaria
Background: Chronic spontaneous urticaria (CSU) is a debilitating disease for which many patients are inadequately treated. However, recent advancements in our understanding of the disease pathophysio...
Read MorePatient Preferences in Topical Psoriasis Treatment
Background: Psoriasis is a common inflammatory skin condition that varies in severity. Most patients have limited disease amenable to topical treatment; however, poor treatment adherence limits effica...
Read MoreUpdate on Hormonal Therapy in Hidradenitis Suppurativa
Hidradenitis suppurativa (HS), a chronic inflammatory disorder of the apocrine-bearing skin, presents with deep seated inflamed nodules, abscesses, draining sinus tracts, and scarring with a profound ...
Read MoreA Multi-Center, Randomized, Blinded Clinical Study Evaluating the Efficacy and Safety of a Novel Topical Product for Facial Dyschromia
Background: Dyschromia can be caused by abnormalities in the increased production and/or reduced clearance of pigmentation in the skin. Causes of hyperpigmentation include excessive sun exposure, medi...
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Features
Self-Reported Long-Term Side Effects of Isotretinoin: A Case Series
Citation: Ghadimi TR, Martinez MJ, Rieder EA. Self-reported long-term side effects of isotretinoin: A case series. J Drugs Dermatol. 2023;22(4):423-424. doi:10.36849/JDD.2303...
Read MoreShining a Light on Vitiligo and Associated Comorbidities: What Is the Evidence?
Citation: Desai S, McCormick E, Sodha P, et al. Shining a light on the vitiligo and associated comorbidities: What is the evidence? J Drugs Dermatol. 2023;22(4):428-430. doi:10.36849/JDD.2023.NVRN0423...
Read MoreBrodalumab: 4-Year US Pharmacovigilance Report
Brodalumab is an interleukin-17 receptor A antagonist approved for the treatment of moderate-to-severe psoriasis in adults without response or with loss of response to other systemic therapies. Brodal...
Read MoreOpen-Label Phase 2 Pilot Study of Oral Tofacitinib in Adult Subjects With Discoid Lupus Erythematosus (DLE)
Citation: Alsukait S, Learned C, Rosmarin D. Open-label phase 2 pilot study of oral tofacitinib in adult subjects with Discoid Lupus Erythematosus (DLE). J Drugs Dermatol. 2023;22(4): 425-427. doi:10....
Read MorePityriasis Alba in Pediatric Patients With Skin of Color
As we continue to work toward a more equitable future of medicine, it is necessary to recognize the needs distinct to pediatric dermatology to decrease health disparities that affect this patient popu...
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Case Reports
Dermal Hypersensitivity Reaction to Semaglutide: Two Case Reports
Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of antidiabetic agents that work by inducing insulin secretion and inhibiting release of glucagon in a glucose-dependent manner. They are ...
Read MoreDupilumab Induced Hair Regrowth in Alopecia Totalis
Alopecia Areata (AA) is an autoimmune process that results in varying degrees of hair loss. Currently, there is no single treatment that has proven to be efficacious in a large cohort of patients. Dup...
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