Issue Archive
May 2022 | Volume 21 | Issue 5
Editorials
Opioid Prescriptions and Pain-Related Patient-Initiated Communication After Mohs Micrographic Surgery: A Retrospective Cohort Study
Background: There is a wide variety in utilization of opioids during Mohs Micrographic Surgery (MMS) despite evidence that a multimodality approach may be more beneficial.
Objective: To evaluate...
Read MoreImpact of the COVID Pandemic on Mohs Micrographic Surgery: A Nationwide Survey
Background: At the onset of the COVID-19 pandemic, many Mohs micrographic surgeries (MMS) were delayed over concerns for propagating further infectious spread and scarcity of medical resources.
...
Read MoreDermatologists' Responses to Benzene Being Reported as a Contaminant in Sunscreen: A Cross-Sectional Analysis
Benzene, a known human carcinogen, was recently found in certain batches of sunscreen products. Our objectives were to analyze the messages conveyed in dermatologists’ social media posts on this...
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Original Articles
Critical Review of the Sentinel Lymph Node Surgery in Malignant Melanoma
Malignant melanoma is one of the most aggressive solid tumors but has low morbidity if treated at an early stage. Over the past decade, the advent of targeted therapy and immunotherapy have productive...
Read MoreOpen-Label Cohort Study to Evaluate Efficacy and Safety of Application of Glycopyrronium Cloth, 2.4% for Palmar Hyperhidrosis
Background: Hyperhidrosis of the palms has a significant negative impact on quality of life. There is no FDA-approved treatment; however, clinicians often use glycopyrronium cloth off-label for this i...
Read MoreSafety and Efficacy of TGF-β1/COX-2 Silencing Therapeutic in Adults With Cutaneous Squamous Cell Carcinoma In Situ
This single-center, open label, dose escalation cohort study evaluated the safety and efficacy of various doses of intralesional injections of TGF-β1/COX-2 combined with histidine-lysine polypept...
Read MoreInsights in Skin of Color Patients With Atopic Dermatitis and the Role of Skincare in Improving Outcomes
Background: Research on the role of race and ethnicity in the pathophysiology of atopic dermatitis (AD) is limited. Variations in the epidemiology, clinical presentation, and disease course in skin of...
Read MoreAntidiabetic Treatment in Patients at High Risk for a Subsequent Keratinocyte Carcinoma
Background: Metformin and sulfonylureas are the most commonly prescribed drugs used for the treatment of type II diabetes. Type II diabetes has been linked to the development of keratinocyte carcinoma...
Read MoreCalcium Hydroxyapatite Filler With Integral Lidocaine CaHA (+) for Soft Tissue Augmentation: Results from an Open-Label Multicenter Clinical Study
Background: Soft tissue augmentation with calcium hydroxylapatite (CaHA) is a versatile technique for line filling, skin tightening, lifting, contouring, and volumizing. The present study was designed...
Read MoreFuture Fungal Fighters in Dermatology: Novel Antifungal Drug Pipeline
Over the last decade, major advances in antifungal drug development have occurred. Novel drugs in the pipeline include ME1111, MAT2203, rezafungin, ibrexafungerp, olorofim, fosmanogepix, MGCD290, VT-1...
Read MoreConsistency in Distribution of Facial Skin Cancers Treated With Mohs Micrographic Surgery
Mohs micrographic surgery (MMS) has become the standard of treatment for skin malignancies of the head and neck. However, there is a paucity of literature describing facial distributions of MMS. Anato...
Read MoreEvaluation of an SPF50 Sunscreen Containing Photolyase and Antioxidants for its Anti-Photoaging Properties and Photoprotection
Background: Background: Skin exposure to ultraviolet radiation (UVR) causes DNA damage, which can lead to mutagenesis, carcinogenesis, cellular death, and photoaging. Signs of photoaging include wrink...
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Features
Mohs Micrographic Surgery in Skin of Color
The United States population is becoming increasingly diverse. Data show increased utilization of Mohs micrographic surgery (MMS) in people of color. Though the incidence of skin cancer in skin of col...
Read MoreIncomplete Staining Artifact: A Confounding Frozen Section Pathology Artifact Encountered During Mohs Micrographic Surgery
The intent of this brief communication is to describe a unique incomplete staining frozen section pathology artifact encountered during Mohs Micrographic Surgery. At the authors’ institution, an...
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Case Reports
Shoreline Nails: A New Nail Sign of SARS-CoV-2 Infection
With the onset of the SARS-CoV-2 pandemic, a number of nail unit changes have been associated with SARS-CoV-2 infection. We report a new unique nail finding within one month of infection and RT-PCR te...
Read MoreKeratinocyte Carcinomas in Immunocompromised Patients Are Reduced After Administration of the Nonavalent Human Papillomavirus Vaccine
Immunosuppression, as seen in solid organ transplant recipients, is highly associated with the development of keratinocyte carcinomas (KCs). Reducing the level of immunosuppression lowers the incidenc...
Read MoreCase Series of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis With Nivolumab and Nivolumab/ Ipilimumab Combination Therapy in Metastatic Melanoma
Nivolumab (anti PD-1 antibody) and ipilimumab (anti CTLA-4 antibody) are immune checkpoint inhibitors (ICI) that effectively stimulate the native T cell response and lead to an antitumor response. The...
Read MoreA Rare Presentation of Dermatofibrosarcoma Protuberans of the Scalp Treated with "Slow-Mohs" Micrographic Surgery
Dermatofibrosarcoma protuberans (DFSP) is a rare, fibrohistiocytic tumor with intermediate malignancy.1 While these tumors are slow-growing and only metastasize in 6% of cases,2 they are often locally...
Read MoreAtopic Dermatitis and the Medications Used for its Management: Impact on Ocular Health
Atopic Dermatitis (AD) is one of the most common inflammatory skin conditions. AD is generally characterized by eczematous and pruritic skin lesions, although it can present differently between indivi...
Read MoreGiant Basal Cell Carcinoma of the Axilla: 8-year Follow-up of a Case Treated with Excision, Vismodegib, and Radiotherapy
Axillary giant basal cell carcinoma is extremely rare and remains challenging for physicians. The few reported cases have a relatively short-term follow-up, and none were treated with an oral hedgehog...
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