Behind the Scenes of Clinical Trials
Next Steps in Derm and the Journal of Drugs in Dermatology, in partnership with the Dermatology Education Foundation (DEF) and Physicians Resources, interviewed Dr. April Armstrong, professor of dermatology and associate dean for clinical research at the Keck School of Medicine at USC. If you’re thinking of getting involved in clinical trials, watch as Dr. Armstrong shares why having the right equipment, space and people are crucial to success. Don’t say yes to every clinical trial protocol! Learn considerations you should take when evaluating research opportunities.
Dr. April Armstrong lectured on this and other topics at the recent DERM2022 NP/PA CME conference held July 28-31, 2022.
Skin of Color Representation in Clinical Trials: An Analysis of Clinicaltrials.gov From 2008-2022
ABSTRACT
There is a plethora of dermatologic clinical trials; however, little is known regarding the representation of skin of color (SOC) populations. We evaluated the 15 most prevalent skin conditions in SOC patients and their representation in clinical trials over 14 years (2008-2022) to address the lack of research regarding dermatologic clinical trials and SOC inclusion. There have been 1,419 clinical trials conducted over the last 14 years regarding the 15 dermatologic conditions most commonly affecting SOC. Despite the prevalence of these conditions in SOC, Black/African American participation was greater than 50% in clinical trials for two conditions, keloids (77.9%) and seborrheic dermatitis (55.3%). Due to the disparities in inclusion, clinical trial data is difficult to extrapolate the results to SOC patients, limiting therapeutic options and potentially contributing to worse outcomes for such patients. Our study confirms that there is limited data available in clinical trials with respect to race, ethnicity, and FST. Further, it highlights how essential it is for SOC to be both adequately represented and reported in research regarding dermatologic skin conditions to ensure equality and equity in dermatologic care.
Assessing Participant Diversity in Acne Clinical Trials
ABSTRACT
A lack of clinical trials devoted specifically to treatment protocols in minority groups and diverse individuals with skin of color (SOC) exists. Treatment decisions often vary based on patient cultural preferences and have differing efficacies based on skin type. As such, it is important to evaluate the diversity of participants being included in dermatology clinical trials.
