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Lindsay OConnor

Oral Collagen Supplementation: A Systematic Review of Dermatological Applications

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Featured Article

800 patients who took up to 10 grams of collagen per day, experienced improvement in skin elasticity, moisture retention, and increased density of collagen fibers in the skin.

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Improvements in skin health is a well-researched benefit of taking collagen – in fact, according to a January 2019 Journal of Drugs in Dermatology study, (recently featured in an Every Day Health article, ” 8 Potential Benefits of Collagen – and 1 Thing it Can’t Do”), 800 patients who took up to 10 grams of collagen per day, experienced improvement in skin elasticity, moisture retention, and increased density of collagen fibers in the skin.

Franchesca D. Choi BS RPh, Calvin T. Sung BS, Margit L.W. Juhasz MD, Natasha Atanaskova Mesinkovska MD PhD

Nutrition is thought to play an important role in skin homeostasis. The use of nutraceuticals or “functional foods” in skincare along with technological innovations within the food industry has been rising.

In 2016, the collagen market was valued at an estimated 3.71 billion USD and is projected to reach 6.63 billion USD by 2025. Collagen supplements, originating from various sources (eg, porcine, bovine, marine) and available in numerous formulations (eg, protein, gelatin, hydrolysate, peptides), are marketed as improving skin integrity and modulating skin aging.

However, even with this increase in patient interest and market share, the use of collagen supplementation in dermatology remains controversial due to the lack of regulation on quality and quantity of ingredients in over-the-counter collagen supplements, as well as minimal peer-reviewed literature on the subject. Fortunately, there are increasing numbers of clinical studies regarding potential effects of collagen-based dietary supplements on skin.

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Oral Collagen Supplementation: A Systematic Review of Dermatological Applications

| Aesthetics, Featured Articles | No Comments
800 patients who took up to 10 grams of collagen per day, experienced improvement in skin elasticity, moisture retention, and increased density of collagen fibers in the skin. Improvements in…

Impact of Iron-Oxide Containing Formulations Against Visible Light-Induced Skin Pigmentation in Skin of Color Individuals

| Aesthetics, Featured Articles, Photoprotection, Skin of Color | No Comments
In this study, the efficacy of two formulations containing iron oxide was evaluated in preventing visible light-induced pigmentation compared with a non-tinted mineral SPF 50+ sunscreen. Hawasatu Dumbuya PhD, Pearl…

Facial Skin Tightening With Microfocused Ultrasound and Dermal Fillers: Considerations for Patient Selection and Outcomes

| Aesthetics, CME Activities, Featured Articles | No Comments
Earn 1.0 CME Credit: Human facial aging is a gradual and ongoing process involving various factors including photodamage, skin laxity, volume loss of subcutaneous tissue, and bony resorption.1 CME CreditHuman…

NEW from the JDD Podcast: “The Science of Sun Protection”

By Photoprotection, Podcast Highlights, Skin Cancer No Comments

JDD Podcast

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How to Listen

The Science of Sun Protection
Part I

Dr. Neal Bhatia and Dr. Adam Friedman

 

Photoprotection works, plain and simple. Yet all too often we must defend good science, dispel unfounded myths, and offer our first born children to get our patients to utilize sunscreen the right way when this behavior directly and primarily benefits them. Why is this and how do we airdrop knowledge in a meaningful way?
In part one of this bonus two part podcast series dedicated to the science and psychology of sunscreen use, AAD Vice President Elect Neal Bhatia, MD joins host Adam Friedman, MD to slather on some practical approaches to communicating sunscreen science and real world use.
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CME Credits Available
This enduring continuing education activity is supported by an independent medical education grant provided by Johnson & Johnson Consumer Inc. 
Participants who earn a minimum, passing grade of 70% would be eligible to receive up to 0.5 credit hours AMA PRA Category 1™ and ANCC credit per podcast. A total of 1 hour for this two-part Sun Protection series.
Learning Objectives:
Upon completion of this enduring, internet-based series of continuing education activities,  participants should be able to:
  • Differentiate features, benefits and limits of chemical and physical sunblocking products
  • Discuss the role of product formulation, delivery vehicle and patient type when recommending sun protection strategies
  • Review multifunctional approaches to photoprotection including use of sunscreen-containing moisturizers and other skin care products
  • Develop strategies leading to effective clinician-patient dialogues to better motivate patients to integrate regular use of sunscreens in their skin care regimen
Take CME Now

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NEW from the JDD Podcast: “The Science of Sun Protection”

| Photoprotection, Podcast Highlights, Skin Cancer | No Comments
iTunes Google Play Stitcher TuneIn Dr. Neal Bhatia and Dr. Adam Friedman   Photoprotection works, plain and simple. Yet all too often we must defend good science, dispel unfounded myths,…

Support the (On)cause: A Practical Review of Supportive Oncodermatology

| Podcast Highlights, Skin Cancer | No Comments
iTunes Google Play Stitcher TuneIn Drs. Mario Lacouture and Adam Friedman   Cancer sucks, plain and simple. What is often overlooked is that the life saving/altering therapies often come with…

Systemic Antibiotics in the Management of Acne: Issues and Considerations for Optimal Care

| Acne, Podcast Highlights | No Comments
iTunes Google Play Stitcher TuneIn Drs. Joslyn Kirby and Adam Friedman   WEEEEEEERE BACK! Join host Dr. Adam Friedman for lively and learned discussion with Dr. Joslyn Kirby on one of the…

Impact of Iron-Oxide Containing Formulations Against Visible Light-Induced Skin Pigmentation in Skin of Color Individuals

By Aesthetics, Featured Articles, Photoprotection, Skin of Color No Comments

Featured Article

In this study, the efficacy of two formulations containing iron oxide was evaluated in preventing visible light-induced pigmentation compared with a non-tinted mineral SPF 50+ sunscreen.

Read more

In this study, the efficacy of two formulations containing iron oxide was evaluated in preventing visible light-induced pigmentation compared with a non-tinted mineral SPF 50+ sunscreen.

Hawasatu Dumbuya PhD, Pearl E Grimes MD, Stephen Lynch PhD, Kalli Ji PhD, Manisha Brahmachary PhD, Qian Zheng Md PhD, Charbel Bouez PhD, Janet Wangari-Talbot PhD

 

 

Visible light (400–700nm), which contributes to 45% of solar radiation, contributes to skin darkening and worsening of dyschromias, particularly in individuals with Fitzpatrick skin phototypes III and higher.

The pathogenesis of melasma is incompletely understood, which poses a challenge for disease management. Causative factors include genetics, ultraviolet (UV) radiation, cosmetics, pregnancy, hormonal therapy, phototoxic drugs, and various medications.

Currently, sunscreens provide limited protection against that spectrum. Due to their capabilities in absorbing, scattering, and reflecting visible light, topical products containing pigments and/or metal oxides can provide additional photoprotection.

In this study, the efficacy of two formulations containing iron oxide was evaluated in preventing visible light-induced pigmentation compared with a non-tinted mineral SPF 50+ sunscreen. Expert grading and colorimetry demonstrated that the iron-oxide containing formulations significantly protected against visible light-induced pigmentation compared to untreated skin or mineral SPF 50+ sunscreen in Fitzpatrick IV individuals.

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Open Access Articles

The Journal of Drugs in Dermatology (JDD) presents Open Access content, unrestricted access to our original articles, award-winning case studies, clinical trial reviews and clearance updates, drugs and devices, and special content geared toward medical residents and other allied health professionals.
Articles are reviewed by the Editorial Board of renowned experts, from key opinion leaders to well-known clinicians. View our open-access dermatology articles now.
View All Open Access Articles

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Oral Collagen Supplementation: A Systematic Review of Dermatological Applications

| Aesthetics, Featured Articles | No Comments
800 patients who took up to 10 grams of collagen per day, experienced improvement in skin elasticity, moisture retention, and increased density of collagen fibers in the skin. Improvements in…

Impact of Iron-Oxide Containing Formulations Against Visible Light-Induced Skin Pigmentation in Skin of Color Individuals

| Aesthetics, Featured Articles, Photoprotection, Skin of Color | No Comments
In this study, the efficacy of two formulations containing iron oxide was evaluated in preventing visible light-induced pigmentation compared with a non-tinted mineral SPF 50+ sunscreen. Hawasatu Dumbuya PhD, Pearl…

Facial Skin Tightening With Microfocused Ultrasound and Dermal Fillers: Considerations for Patient Selection and Outcomes

| Aesthetics, CME Activities, Featured Articles | No Comments
Earn 1.0 CME Credit: Human facial aging is a gradual and ongoing process involving various factors including photodamage, skin laxity, volume loss of subcutaneous tissue, and bony resorption.1 CME CreditHuman…

Support the (On)cause: A Practical Review of Supportive Oncodermatology

By Podcast Highlights, Skin Cancer No Comments

JDD Podcast

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How to Listen

Support the (On)cause: A Practical Review of Supportive Oncodermatology

Drs. Mario Lacouture and Adam Friedman

 

Cancer sucks, plain and simple. What is often overlooked is that the life saving/altering therapies often come with substantial baggage adding to this proclamation with skin, hair, and nail adverse events significantly impacting quality of life and even treatment course.
Enter supportive oncodermatology, and along with it the mastermind behind this rapidly emerging field, Dr. Mario Lacouture, Professor and Director of the Oncodermatology Program in the Dermatology Service, Department of Medicine, at Memorial Sloan Kettering Cancer Center in New York City.
Dr. Lacatoure joins podcast host Dr. Adam Friedman to discuss the array of cutaneous clusters that not only can, but are almost expected to occur during cancer therapy. Learn how even simple OTC products can contribute to both ameliorating and even preventing some of these sequelae. Understand how you (yeah, I’m talkin’ to you) can make an extraordinary impact in these patients’ lives. Tune in to this podcast to support your supportive oncoderm fund of knowledge.
This podcast was supported by Johnson & Johnson Consumer Inc.
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Upcoming Related Supplement:
  • The Biological Impact of Oats: Eczema and Beyond
  • Blair Allais MD and Adam Friedman MD FAAD
  • Department of Dermatology, George Washington School of Medicine and Health Sciences, Washington, DC
  • October 2020 | Volume 19 | Issue 10 | Supplement| Copyright © October 2020

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NEW from the JDD Podcast: “The Science of Sun Protection”

| Photoprotection, Podcast Highlights, Skin Cancer | No Comments
iTunes Google Play Stitcher TuneIn Dr. Neal Bhatia and Dr. Adam Friedman   Photoprotection works, plain and simple. Yet all too often we must defend good science, dispel unfounded myths,…

Support the (On)cause: A Practical Review of Supportive Oncodermatology

| Podcast Highlights, Skin Cancer | No Comments
iTunes Google Play Stitcher TuneIn Drs. Mario Lacouture and Adam Friedman   Cancer sucks, plain and simple. What is often overlooked is that the life saving/altering therapies often come with…

Systemic Antibiotics in the Management of Acne: Issues and Considerations for Optimal Care

| Acne, Podcast Highlights | No Comments
iTunes Google Play Stitcher TuneIn Drs. Joslyn Kirby and Adam Friedman   WEEEEEEERE BACK! Join host Dr. Adam Friedman for lively and learned discussion with Dr. Joslyn Kirby on one of the…

View the Latest Discoveries in Skin Cancer Research

By Skin Cancer No Comments

Dermatology Resource Centers

JDD Resource Centers

Stay up-to-date on new clinical findings in Skin Cancer  View the latest articles, case reports, supplements, Podcast episodes and more!

Skin Cancer Resource Center

The Latest Clinical Findings in Skin Cancer

Discover the latest research in Skin Cancer: introducing the JDD Skin Cancer Resource Center.

Review clinical findings, articles, case reports, supplements, podcast episodes and more.

Skin Cancer Articles

  • Impact of a 31-gene Expression Profiling Test for Cutaneous Melanoma on Dermatologists’ Clinical Management Decision

    Following a diagnosis of cutaneous malignant melanoma (CMM), patients are often guided for subsequent management by their dermatologist and national guideline recommendations. Based upon staging classification for CMM, guidelines recommend diagnostic tests and additional evaluation which may provide defined treatment protocols, surveillance, and follow-up.

     

  • A Randomized Trial of Broad Area ALA–PDT for Field Cancerization Mitigation in High-Risk Patients

    Actinic keratoses (AKs) are precancerous, dysplastic epidermal lesions with potential for progression to squamous cell carcinoma (SCC). A study by Criscione et al1 revealed that in a high-risk population (≥2 keratinocyte carcinomas in previous 5 years), approximately 65% of all primary SCCs arose in lesions previously diagnosed as AKs. Furthermore, it demonstrated that the risk of malignant progression of AKs to primary SCC increases over time (0.6% at 1 year and 2.6% at 4 years).1 Cellular damage and atypia seen histologically in AKs are similar to those of surrounding nonlesional skin,2,3 suggesting that skin surrounding AKs may have an increased risk of skin cancer.

     

  • Multiple Primary Melanomas Occurring Around the Same Time: A Review of Terminology and Implications

    Multiple primary melanomas (MPMs) have been reported to occur in 2-10% of melanoma patients. This study conducted a review of the literature to elucidate the definitions of terminology used to describe MPMs that were diagnosed in close temporal proximity as well as explore common risk factors. Terminology found in the literature included “concurrent”, “simultaneous” and “synchronous” with varying definitions that ranged from 0-6 months between diagnoses of the first and subsequent melanomas. Eight cases are described in chronological order, and the incidence of MPMs diagnosed around the same time were reported as 22-39%. Nevus spilus was identified as a potential risk factor for MPMs. This study highlights that MPMs are not uncommon, and clinicians should remain aware that MPMs can be diagnosed at or around the same time, warranting thorough skin exams.

 
View All Skin Cancer Articles

Case Reports

  • Basal Cell Carcinoma in the Nasal Vestibule

    Basal cell carcinomas (BCC) arise from DNA damage to cells of the basal layer of the epidermis and most commonly in areas of the skin exposed to sunlight or ultraviolet radiation. BCC is the most common skin cancer seen in humans with over 4.3 million cases reported in the United States and is responsible for 3-10% of all cancers annually. We report what we believe to be the first case of this very prevalent skin cancer arising in the nasal vestibule. The lesion was treated with Mohs micrographic surgery and required three stages to obtain histological clearance. Given the location of the tumor, Mohs surgery was chosen due to the procedure’s effectiveness for achieving the highest cure rate with the lowest incidence of tumor recurrence and for preserving as much adjacent healthy tissue as possible

     

  • Combination Topical Chemotherapy for the Treatment of an Invasive Cutaneous Squamous Cell Carcinoma

    Standard of care for squamous cell carcinoma (SCC) is usually surgical, with either excision or Mohs micrographic surgery. However, surgery may not be ideal for elderly patients with numerous lesions, who are poor surgical candidates or who refuse surgery. Topical 5-fluorouracil (5-FU) and imiquimod have been studied off-label as monotherapies in the treatment of SCC in situ with promising results. However, long-term tumor-free survival rates are still less than with surgical management.

     

  • Recurrent Squamous Cell Carcinoma Arising Within a Linear Porokeratosis

    Here we report a case of linear porokeratosis with recurrent malignant degeneration to squamous cell carcinoma (SCC) recurring six years after excision of initial SCC. A 79-year-old woman presented with a friable tumor located within a longstanding lesion on her posterior thigh. Six years prior, she was diagnosed with SCC arising within the same lesion, which had been surgically excised with negative margins. Physical examination revealed a 3.5 x 2.7 cm friable tumor on the left proximal posterior thigh.

 
View All Skin Cancer Case Reports

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NEW from the JDD Podcast: “The Science of Sun Protection”

| Photoprotection, Podcast Highlights, Skin Cancer | No Comments
iTunes Google Play Stitcher TuneIn Dr. Neal Bhatia and Dr. Adam Friedman   Photoprotection works, plain and simple. Yet all too often we must defend good science, dispel unfounded myths,…

Support the (On)cause: A Practical Review of Supportive Oncodermatology

| Podcast Highlights, Skin Cancer | No Comments
iTunes Google Play Stitcher TuneIn Drs. Mario Lacouture and Adam Friedman   Cancer sucks, plain and simple. What is often overlooked is that the life saving/altering therapies often come with…

View the Latest Discoveries in Skin Cancer Research

| Skin Cancer | No Comments
Stay up-to-date on new clinical findings in Skin Cancer  View the latest articles, case reports, supplements, Podcast episodes and more!Discover the latest research in Skin Cancer: introducing the JDD Skin…

Facial Skin Tightening With Microfocused Ultrasound and Dermal Fillers: Considerations for Patient Selection and Outcomes

By Aesthetics, CME Activities, Featured Articles No Comments

CME Activities

Earn 1.0 CME Credit: Human facial aging is a gradual and ongoing process involving various factors including photodamage, skin laxity, volume loss of subcutaneous tissue, and bony resorption.

Take CME Now

Human facial aging is a gradual and ongoing process involving various factors including photodamage, skin laxity, volume loss of subcutaneous tissue, and bony resorption.

As the aging US population is growing, minimally invasive strategies have become the primary treatment modalities for addressing mild to moderate age-related facial changes. The introduction of microfocused ultrasound (MFU) represents a method to produce a deeper wound healing response with increased collagen remodeling and more durable clinical response. MFU-V treatment protocols continue to be refined and use in combination with other minimally invasive strategies including injectable dermal fillers such as diluted calcium hydroxylapatite for skin laxity and appearance of lines in the neck and décolletage has been studied.

Need exists for expanded understanding of dermatology providers on the application of microfocused ultrasound in combination with injectable dermal fillers as a treatment approach for lifting skin on the neck and face and for improving lines and wrinkles on the chest

CME Certificate Information

  • This CME examination requires a 70% pass mark to receive the CME credit and certificate.
  • This activity is supported by an educational grant provided by Galderma Laboratories, L.P.

Upon completion of this continuing education activity participants should be able to:

  • Summarize the mechanism of action of high-resolution ultrasound imaging (MFU-V) for lifting skin on the neck and face, improving lines and wrinkles on the chest and improving collagen synthesis
  • Identify patients best suited for treatment with MFU-V in combination with injectable dermal fillers
  • Compare features, benefits, and safety profile MFU-V treatment in lifting skin on the neck and face and for improving lines and wrinkles on the chest
Take CME Now

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Facial Skin Tightening With Microfocused Ultrasound and Dermal Fillers: Considerations for Patient Selection and Outcomes

| Aesthetics, CME Activities, Featured Articles | No Comments
Earn 1.0 CME Credit: Human facial aging is a gradual and ongoing process involving various factors including photodamage, skin laxity, volume loss of subcutaneous tissue, and bony resorption.1 CME CreditHuman…

Expiring Soon: Capturing Consensus and Cutting Out Misconceptions regarding the Aesthetic Skin of Color Consumer

| CME Activities | No Comments
0.5 CME Credits Who knows what’s best/worst for facial aesthetics in the skin of color patient? No really who? Because there is a great deal of folklore and ballyhoo related…

Re-examining the Optimal Use of Neuromodulators and the Changing Landscape: A Consensus Panel Update

| CME Activities | No Comments
1 CME CreditSince initial US Food and Drug Administration approval of botulinum toxin type A (BoNT-A) for aesthetic use in 2002, clinical evidence and experience with BoNT-A and understanding of…

View the Latest Discoveries in Aesthetics, Anti-Aging, and Medical Dermatology

By Featured Articles, JDD Highlights No Comments

JDD Highlights

September JDD

The September issue of the Journal of Drugs in Dermatology is available now. This month, we focus on aesthetic treatments, with special features on Public Health, Anti-aging, Aesthetic, and Medical Dermatology.

Read the September JDD Now

Aesthetics, Public Health, Anti-Aging, and Medical Dermatology

The September issue of the Journal of Drugs in Dermatology is available now. This month, we focus on aesthetic treatments, with special features on Public Health, Anti-aging, Aesthetic, and Medical Dermatology.

Article Highlights

 

Editor's Picks

 

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Oral Collagen Supplementation: A Systematic Review of Dermatological Applications

| Aesthetics, Featured Articles | No Comments
800 patients who took up to 10 grams of collagen per day, experienced improvement in skin elasticity, moisture retention, and increased density of collagen fibers in the skin. Improvements in…

NEW from the JDD Podcast: “The Science of Sun Protection”

| Photoprotection, Podcast Highlights, Skin Cancer | No Comments
iTunes Google Play Stitcher TuneIn Dr. Neal Bhatia and Dr. Adam Friedman   Photoprotection works, plain and simple. Yet all too often we must defend good science, dispel unfounded myths,…

Impact of Iron-Oxide Containing Formulations Against Visible Light-Induced Skin Pigmentation in Skin of Color Individuals

| Aesthetics, Featured Articles, Photoprotection, Skin of Color | No Comments
In this study, the efficacy of two formulations containing iron oxide was evaluated in preventing visible light-induced pigmentation compared with a non-tinted mineral SPF 50+ sunscreen. Hawasatu Dumbuya PhD, Pearl…

Topical Cannabinoids for the Management of Psoriasis Vulgaris: Report of a Case and Review of the Literature

By Featured Articles, Psoriasis No Comments

Featured Article

The interest in use of medical cannabis for chronic dermatologic conditions such as psoriasis, eczema, and acne has been growing mostly owing to rapidly emerging decriminalization across the country and impressive commercially driven popularization of a variety of cannabinoid preparations including topical forms such as creams, salves, lotions, lubricants, and many others.

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This report details a case of a young man with psoriasis managed with topical cannabinoids.

Adam J. Friedman MD, Kimia Momeni BS, Mikhail Kogan MD

 

The interest in use of medical cannabis for chronic dermatologic conditions such as psoriasis, eczema, and acne has been growing mostly owing to rapidly emerging decriminalization across the country and impressive commercially driven popularization of a variety of cannabinoid preparations including topical forms such as creams, salves, lotions, lubricants, and many others.

However, while the market is exponentially growing, the rate at which mechanistic and clinical evidence supporting the use of cannabinoids in a litany of diseases is significantly slower. In fact, Robinson et al highlighted significant gaps in dermatologists understanding of the biology of cannabinoids and comfort with this space, further highlighting the great need to disseminate information throughout the medical community.

Along this vein, we present a case of a young man with psoriasis managed with topical cannabinoids.

View Case Study Now
Article Cited in this Post

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Oral Collagen Supplementation: A Systematic Review of Dermatological Applications

| Aesthetics, Featured Articles | No Comments
800 patients who took up to 10 grams of collagen per day, experienced improvement in skin elasticity, moisture retention, and increased density of collagen fibers in the skin. Improvements in…

Impact of Iron-Oxide Containing Formulations Against Visible Light-Induced Skin Pigmentation in Skin of Color Individuals

| Aesthetics, Featured Articles, Photoprotection, Skin of Color | No Comments
In this study, the efficacy of two formulations containing iron oxide was evaluated in preventing visible light-induced pigmentation compared with a non-tinted mineral SPF 50+ sunscreen. Hawasatu Dumbuya PhD, Pearl…

Facial Skin Tightening With Microfocused Ultrasound and Dermal Fillers: Considerations for Patient Selection and Outcomes

| Aesthetics, CME Activities, Featured Articles | No Comments
Earn 1.0 CME Credit: Human facial aging is a gradual and ongoing process involving various factors including photodamage, skin laxity, volume loss of subcutaneous tissue, and bony resorption.1 CME CreditHuman…

The Therapeutic Use of Antioxidants for Melasma

By Aesthetics No Comments

Featured Article

With a well demonstrated impact on quality of life, melasma is a common cause for seeking dermatologic care. There is no universally efficacious therapy, so combination treatment is preferred. Therapies include topical hypopigmenting agents, laser treatment, microneedling, chemical peels, radiofrequency, and oral medications.1 Furthermore, it is critical for patients to avoid exacerbating factors.

Read more

In this review, authors discuss the well-defined role of oxidative stress in melasma and the therapeutic efficacy of various antioxidants for patients suffering from melasma, focusing on studies investigating the role of vitamin C, azelaic acid, cysteamine, glutathione, carotenoids, and numerous other antioxidants in disorders of hyperpigmentation.

Kayla M. Babbush BS, Remy A. Babbush BS, Amor Khachemoune MD FAAD FACMS

 

Melasma is a chronic and acquired skin disorder of hyperpigmentation that presents with symmetric hypermelanosis of sun exposed areas, especially the face. Disease prevalence, ranging from 1 to 50%, varies with gender, ethnicity, skin phenotype, and sun exposure.

The pathogenesis of melasma is incompletely understood, which poses a challenge for disease management. Causative factors include genetics, ultraviolet (UV) radiation, cosmetics, pregnancy, hormonal therapy, phototoxic drugs, and various medications.

Melasma is evaluated by Melasma Area and Severity Index (MASI) score, modified MASI (mMASI) score, Melasma Quality of Life Scale (MelasQoL), colorimetry, and mexametry.

With a well demonstrated impact on quality of life, melasma is a common cause for seeking dermatologic care. There is no universally efficacious therapy, so combination treatment is preferred. Therapies include topical hypopigmenting agents, laser treatment, microneedling, chemical peels, radiofrequency, and oral medications.1 Furthermore, it is critical for patients to avoid exacerbating factors.

The skin, a protective organ critical in homeostasis, is the site of numerous biochemical processes, including the generation of free radicals, namely reactive oxygen and nitrogen species. Reactive oxygen species (ROS) are necessary for biological signaling processes, but, in excess, ROS can damage biomolecules.3 There is clear evidence of oxidative stress in melasma.

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Article Cited in this Post

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Oral Collagen Supplementation: A Systematic Review of Dermatological Applications

| Aesthetics, Featured Articles | No Comments
800 patients who took up to 10 grams of collagen per day, experienced improvement in skin elasticity, moisture retention, and increased density of collagen fibers in the skin. Improvements in…

Impact of Iron-Oxide Containing Formulations Against Visible Light-Induced Skin Pigmentation in Skin of Color Individuals

| Aesthetics, Featured Articles, Photoprotection, Skin of Color | No Comments
In this study, the efficacy of two formulations containing iron oxide was evaluated in preventing visible light-induced pigmentation compared with a non-tinted mineral SPF 50+ sunscreen. Hawasatu Dumbuya PhD, Pearl…

Facial Skin Tightening With Microfocused Ultrasound and Dermal Fillers: Considerations for Patient Selection and Outcomes

| Aesthetics, CME Activities, Featured Articles | No Comments
Earn 1.0 CME Credit: Human facial aging is a gradual and ongoing process involving various factors including photodamage, skin laxity, volume loss of subcutaneous tissue, and bony resorption.1 CME CreditHuman…

Increased Trend of Cosmetic Procedures in Patients With Psoriasis Who Attain 75% or Greater Improvement

By Aesthetics, Featured Articles No Comments

Featured Article

A survey was conducted at a single dermatology center to determine if there was an increased trend in cosmetic procedures in patients with moderate to severe psoriasis who attained 75% or greater reduction of the body surface area (BSA) with biologic agents and oral systemic therapies, and if this was related to an improvement in quality of life following psoriasis clearance.

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A survey was conducted at a single dermatology center to determine if there was an increased trend in cosmetic procedures in patients with moderate to severe psoriasis who attained 75% or greater reduction of the body surface area (BSA) with biologic agents and oral systemic therapies, and if this was related to an improvement in quality of life following psoriasis clearance.

Michelle E. Walters MD, Delphine J. Lee MD PhD, Paul S. Yamauchi MD PhD

Psoriasis is a chronic skin condition with a negative impact on patient quality of life. The National Psoriasis Foundation states that an acceptable response to psoriasis treatment is at least a 75% reduction in body surface area (BSA) at 3 months after initiation of treatment.

This reduction in BSA has been associated with improvement in quality of life, with clearance rates of clear to almost clear leading to an even greater improvement in quality of life.2,3 To date, there have been no studies examining the relationship between improvement in quality of life following a reduction in BSA, and the increased utilization of cosmetic procedures. Here, we examine the relationship between quality of life and the use of various cosmetic procedures in patients treated for psoriasis with systemic and biologic therapies who achieved at least 75% reduction in BSA.

This was a retrospective study assessing quality of life and the use of cosmetic procedures in psoriasis patients after attaining a75% or greater reduction of the body surface area with biologic agents only, systemic agents only, or a combination of both. This study was conducted according to the ethical guidelines of the 1975 Declaration of Helsinki. All patients provided informed consent.

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Article Cited in this Post

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Oral Collagen Supplementation: A Systematic Review of Dermatological Applications

| Aesthetics, Featured Articles | No Comments
800 patients who took up to 10 grams of collagen per day, experienced improvement in skin elasticity, moisture retention, and increased density of collagen fibers in the skin. Improvements in…

Impact of Iron-Oxide Containing Formulations Against Visible Light-Induced Skin Pigmentation in Skin of Color Individuals

| Aesthetics, Featured Articles, Photoprotection, Skin of Color | No Comments
In this study, the efficacy of two formulations containing iron oxide was evaluated in preventing visible light-induced pigmentation compared with a non-tinted mineral SPF 50+ sunscreen. Hawasatu Dumbuya PhD, Pearl…

Facial Skin Tightening With Microfocused Ultrasound and Dermal Fillers: Considerations for Patient Selection and Outcomes

| Aesthetics, CME Activities, Featured Articles | No Comments
Earn 1.0 CME Credit: Human facial aging is a gradual and ongoing process involving various factors including photodamage, skin laxity, volume loss of subcutaneous tissue, and bony resorption.1 CME CreditHuman…

Expiring Soon: Capturing Consensus and Cutting Out Misconceptions regarding the Aesthetic Skin of Color Consumer

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CME Activities

"Capturing Consensus and Cutting Out misConceptions regarding the Aesthetic Skin of Color Consumer"

Who knows what’s best/worst for facial aesthetics in the skin of color patient? No really who? Because there is a great deal of folklore and ballyhoo related to what one can and cannot do, forgetting even what the patients think.
Enter Dr. Andrew Alexis, Professor and Chair of the Department of Dermatology at Mount Sinai St. Luke’s and Mount Sinai West and Director of the Skin of Color Center, with his experienced SOC entourage to marry personal experience and evidence (what a beautiful couple!).
Tune in to hear how it all went down. You couldn’t be in the room where it happened, but after this podcast you might have well been. Learn from one of the greats as I pick his brain on all things, medical and aesthetic, SOC. C to it you don’t miss this podcast.

To receive a CME certificate of participation, you should:

  • Listen to the Podcast Episode here
  • This CME examination requires a 70% pass mark to receive the CME credit and certificate.

Following online completion of the posttest and evaluation, a certificate of participation will be available for download/printing immediately.

Take CME Now

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Facial Skin Tightening With Microfocused Ultrasound and Dermal Fillers: Considerations for Patient Selection and Outcomes

| Aesthetics, CME Activities, Featured Articles | No Comments
Earn 1.0 CME Credit: Human facial aging is a gradual and ongoing process involving various factors including photodamage, skin laxity, volume loss of subcutaneous tissue, and bony resorption.1 CME CreditHuman…

Expiring Soon: Capturing Consensus and Cutting Out Misconceptions regarding the Aesthetic Skin of Color Consumer

| CME Activities | No Comments
0.5 CME Credits Who knows what’s best/worst for facial aesthetics in the skin of color patient? No really who? Because there is a great deal of folklore and ballyhoo related…

Re-examining the Optimal Use of Neuromodulators and the Changing Landscape: A Consensus Panel Update

| CME Activities | No Comments
1 CME CreditSince initial US Food and Drug Administration approval of botulinum toxin type A (BoNT-A) for aesthetic use in 2002, clinical evidence and experience with BoNT-A and understanding of…

Post-Inflammatory Hyperpigmentation: A Review of Treatment Strategies

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Featured Article

Post-inflammatory hyperpigmentation (PIH) is a reactive process resulting from increased melanin or abnormal distribution of melanin secondary to inflammatory skin conditions, dermatologic therapies, and external stimuli. Because PIH is a common condition that has a substantial effect on the quality of life, an understanding of its treatment modalities is essential. Though there are many therapeutic strategies for hyperpigmentary conditions such as melasma that are described in the literature, fewer studies focus on PIH. This article aims to provide a comprehensive literature review of therapies specifically used to treat PIH, such as topical combinations, chemical peels, and lasers.

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This article aims to provide a comprehensive literature review of therapies specifically used to treat PIH, such as topical combinations, chemical peels, and lasers.

Adele Shenoy BA, Raman Madan MD

Post-inflammatory hyperpigmentation (PIH) is a reactive process resulting from increased melanin or abnormal distribution of melanin, secondary to inflammatory skin conditions such as acne, atopic dermatitis, contact dermatitis, and psoriasis, as well as external factors such as burns and radiation therapy. An understanding of treatment strategies for PIH is essential, as it has a large impact on the quality of life.

Though there are many therapeutic strategies for hyperpigmentary conditions such as melasma that are described in the literature, fewer studies specifically address PIH. Thus, we conducted a literature review on PubMed using key words “post-inflammatory hyperpigmentation” OR “postinflammatory hyperpigmentation.”

Studies that did not specifically address PIH and articles that were not published in English were excluded. Additional studies were obtained by scanning references. This review adds to the current literature by discussing the evidence for topical therapies, chemical peels, and laser therapy used specifically for hyperpigmentation from PIH.

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