Worsening Injection Site Reactions with Continued Use of Etanercept

March 2003 | Volume 2 | Issue 2 | Case Reports | 184 | Copyright © March 2003

Kimberly R. Edwards, MD; Christen M. Moward, MD and Wiiliam B. Tyler, MD

We report the case of a patient with persistent and worsening injection site reactions associated with subcutaneous etanercept therapy. Injection site reactions are well documented to occur early in therapy; however they typically decrease in frequency over time. This patient developed early injection site reactions that have persisted and worsened into his tenth month of treatment with etanercept.