US Cutaneous Oncodermatology Management (USCOM): A Practical Algorithm

September 2021 | Volume 20 | Issue 9 | Supplement Individual Articles | 3ss | Copyright © September 2021

Published online September 1, 2021

Mario E. Lacouture MD,a Jennifer Choi MD,b Alice Ho MD,c Jonathan Leventhal MD,d Beth N. McLellan MD,e Anneke Andriessen PhD,f Maxwell B. Sauder MD,g Edith Mitchell MDh

aOncodermatology, Memorial Sloan Kettering Cancer Center, New York, NY
bOncodermatology Program, Department of Dermatology, Northwestern University Feinberg School of Medicine, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL
cRadiation Oncology, Massachusetts General Hospital, Memorial Sloan Kettering Cancer Center, New York, NY
dOncodermatology, Smilow Cancer Hospital at Yale, New Haven, CT
eMontefiore's Division of Dermatology and Montefiore Einstein Center for Cancer Care; Dermatology, Jacobi Medical Center, New York, NY fRadboud UMC, Nijmegen and Andriessen Consultants, Malden, The Netherlands
gOncodermatology, Princess Margaret Cancer Centre, Pigmented Lesion Clinic, Toronto Dermatology Disparities; Gastrointestinal Centre, Toronto, ON, Canada
hCenter to Eliminate Cancer Disparities, Gastrointestinal Oncology, Thomas Jefferson University Hospital and Jefferson Methodist Hospital, Philadelphia, PA

access to specialized multidisciplinary oncology teams may not be available.


A small panel of physicians developed the algorithm, representing a few centers, and did not include patients in the development. While alternatives for prevention and management of cAEs could exist, the statements are suggestions for best practice developed from a panel of expert clinicians supported by peer-reviewed literature. Although limited evidence was available to guide the development of the algorithm, the project will hopefully encourage more skincare studies to prevent and treat cAEs.


A multidisciplinary team treating and guiding the cancer patient may improve cancer treatment tolerance. The USCOM algorithm on general skincare measures, including cleansers and moisturizers to prevent or reduce the severity of cAEs, may increase awareness and help improve cancer patient outcomes.


The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by unrestricted educational grant from La Roche-Posay US. Dr. Lacouture has a consultant role with Johnson and Johnson, Novocure, QED, Bicara, Janssen, Novartis, F. Hoffmann-La Roche AG, EMD Serono, Astrazeneca, Innovaderm, Deciphera, DFB, Azitra, Kintara, RBC/La Roche Posay, Trifecta, Varsona, Genentech, Loxo, Seattle Genetics, Lutris, OnQuality, Azitra, Roche, Oncoderm, NCODA, Apricity. Dr. Lacouture also receives research funding from Lutris, Paxman, Novocure, J&J, US Biotest, OQL, Novartis and AZ and is funded in part through the NIH/NCI Cancer Center Support Grant P30 CA008748.

All authors contributed to the development of this work and its review and agreed with its content.


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