Treatment of Recalcitrant Verruca Vulgariswith Candida Antigen in Patient With HumanImmunodeficiency Virus

Verruca vulgaris is often difficult to treat in individuals with human immunodeficiency virus (HIV) infection. We present a case of an HIV positive 44 year-old male with a 3-year history of multiple recalcitrant verruca vulgaris involving his hands and face. He did not respond to cryotherapy, urea 40% cream, imiquimod 5% cream, paring, intralesional bleomycin, salicylic acid 6% gel, and electrodesiccation and curettage. The patient achieved complete clearance of all warts within 1 month following treatment of his hands with intralesional Candida antigen. This case reports a complete response of verruca vulgaris to intralesional Candida antigen in an immunocompromised patient.