Treatment of Papulopustular RosaceaWith Sodium Sulfacetamide 10%/Sulfur 5%Emollient Foam
March 2009 | Volume 8 | Issue 3 | Case Reports | 299 | Copyright © March 2009
Mark W. Trumbore PhD, Jay A. Goldstein MD, Ronald M.Gurge PhD
Abstract
Acne rosacea is a chronic cutaneous disorder affecting as many as 14 million Americans. Papulopustular rosacea is the classic form
of rosacea characterized by papules, pustules, and erythema. The skin barrier deficiency and vascular hyperactivity characteristic of
papulopustular rosacea increase skin dryness and irritation, which can be further exacerbated by medications commonly used to treat
rosacea. Sodium sulfacetamide 10%/sulfur 5% emollient foam (SSSE foam) is formulated for topical administration and is fragrance
free and alcohol free. This nonrandomized, noncontrolled, open-label, prospective case series was designed to evaluate the efficacy
and safety of a SSSE foam for the treatment of papulopustular rosacea in 8 patients. Patients experienced clinically significant improvements
in the severity of rosacea with a favorable safety profile, and reported of an improved quality of life. The high patient satisfaction
ratings for SSSE foam suggest that the product may improve long-term compliance rates, with the potential to yield more favorable
clinical outcomes.