Treating Sunken Upper Eyelid With Hyaluronic Acid: Recommendations and Results

September 2022 | Volume 21 | Issue 9 | 1002 | Copyright © September 2022


Published online August 25, 2022

Julieta Spada MD

Private Practice, Dermatología y Estética, Buenos Aires, Argentina

Abstract
Background: Supraorbital hollowness is a feature that gives an unesthetic, aged, and cadaveric aspect to the eyelids. This complex anatomic area is affected by different variables. Treating this area with fillers poses a real challenge in terms of reducing risks and predicting natural results. We aimed to report outcomes observed in patients treated with injections of hyaluronic acid (HA) soft tissue fillers. Additionally, we have reviewed sunken upper eyelid (SUE) anatomy, etiology, and pathophysiology with the objectives of describing a new classification of SUE, showing a lower risk technique to fill the area, and explaining the importance of using a high cohesivity HA product.
Methods: We included 32 adults (96.9% female) without previous fillers in the area, who were injected with HA (Belotero Balance) with a 25 G, 40 mm blunt cannula. The procedure was fractionated in 2/3 visits. The assessment was performed at day 0, day 14, day 30, and day 365 with standard camera and Vectra H2 (Canfield).
Results: All patients treated with HA showed natural results without significant edema on day 30. Only 1 patient (3.1%) required hyaluronidase injections to dissolve overcorrection of the area on day 14. No severe complications were observed. For most patients, obtained results remained stable on day 365.
Conclusion: As SUE is one of the most prominent signs of aging, the desire for rejuvenation and the popularity of non-surgical solutions have increased. We present our results with a cohesive HA as a highly suitable filler for SUE. Given the high patient satisfaction, long-lasting results, and reduced complication risk, our presented approach may represent a safe and effective novel treatment strategy.

J Drugs Dermatol. 2022;21(9):1002-1008. doi:10.36849/JDD.6745R1

INTRODUCTION

Supraorbital hollowness is a feature that gives an unesthetic, aged, and cadaveric aspect to the eyelids, giving the impression of fatigue even if the person is well rested (Figure 1).1 This deformity may be referred to as an A-frame deformity, superior sulcus syndrome, upper eyelid hollowing, sunken superior sulcus, or sunken upper eyelid (SUE).1-2 We consider this last definition the most appropriate term to describe this condition, and SUE has therefore been used throughout this paper.

There are several changes induced by aging in the upper eyelid.1-3 Atrophy of the orbital fat is one of the most noticeable features of aging.1-3 The skin manifests dermatochalasis, or laxity, due to elastosis and thinning, and the lacrimal glands can become ptotic.4 This ptosis is called senile ptosis and appears frequently together with the skin softening, dynamic wrinkles, and hyperpigmentation of the skin resulting from solar exposure.5 The width and length of the orbital fissure change over time, and both the vertical palpebral and the horizontal palpebral fissures decrease gradually.6 Age-related bone resorption of the orbits is most significant in the inferolateral and superiomedial sides, essentially contributing to the palpebromalar groove and the SUE respectively.26 All these changes may occur earlier in patients with high radix and pronounced frontal bone.7

Since SUE is frequently the first sign of aging noted by a patient and one of the first areas capturing people’s attention, the desire to rejuvenate the aging SUE is constantly increasing.6-8 Replacing lost volume may provide the treated patient with less evidence of aging, thus essentially giving them a powerful