The Usefulness of Narrowband UV B as a Monotherapy for the Treatment of Chronic Plaque Psoriasis

Objective: To assess the efficacy and safety of narrowband ultraviolet B (UVB) phototherapy in dark-skinned Saudi patients with chronic plaque psoriasis. Patients and Methods: This prospective study was performed on 63 patients of chronic plaque psoriasis attending Qassim University clinics from May 2004 through June 2009. Narrowband UVB irradiation was done three times per week using the 311±2 nm wavelength. Results: Approximately 79 percent of patients achieved disease clearance (i.e., 90% or more reduction in PASI scores). The response to treatment was significantly better in females compared to males. No serious side effects were observed. Conclusion: The narrowband UVB phototherapy was found to be safe and effective in darker-skinned Saudi patients with chronic plaque psoriasis, especially among females. A longer period of treatment (minimum of six months) is recommended for complete clearance of psoriasis.