The Use of Photodynamic Therapy in Dermatology: Results of a Consensus Conference
February 2006 | Volume 5 | Issue 2 | Original Article | 140 | Copyright © February 2006
Mark S. Nestor MD PhD (chair), Michael H. Gold MD (co-chair), Arielle N. B. Kauvar MD, Amy F. Taub MD, Roy G. Geronemus MD, Eva C. Ritvo MD, Dore J. Gilbert MD, Mitchel P. Goldman MD, Donald F. Richey MD
Abstract
Photodynamic therapy (PDT) has significant promise in improving outcomes of patients with a variety of cutaneous conditions.
A group of experts met to review the principles, indications, and clinical benefits of PDT with 5-aminolevulinic
acid (ALA). They also reviewed PDT with methyl aminolevulinate. The experts established consensus statements for pretreatment,
posttreatment, ALA contact time, light sources, and numbers of sessions associated with ALA PDT for actinic
keratosis and superficial basal cell carcinoma, photorejuvenation and cosmetic enhancement, acne, sebaceous skin, rosacea,
and rhinophyma. They based consensus recommendations on their clinical experience and the medical literature. They also
suggested future applications of ALA PDT. Experts concluded that ALA PDT is a safe and effective modality for the treatment
of conditions commonly encountered in dermatology. Since downtime is minimal, the technique is suitable for
patients of all ages and lifestyles. Appropriate light sources are available in many dermatology offices. The expanding clinical
and financial benefits of PDT justify the purchase of an appropriate light source.