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Jan 31
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INDIVIDUAL ARTICLE: Insights on the Impact of Scalp Barrier Condition on Hair Health

By Chuck Lin No Comments
INTRODUCTIONResearch has shown that scalp and hair health are connected, but the link is not yet fully understood or characterized. Hair growth begins within the hair follicle, about 4 mm…
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Jan 31
Love0

INDIVIDUAL ARTICLE: Appraisal of Ruxolitinib 1.5% Cream as a First-Line Topical Therapeutic Agent for Adolescents and Adults With Mild-to-Moderate Atopic Dermatitis

By Chuck Lin No Comments
INTRODUCTIONThe topical therapeutic landscape of atopic dermatitis (AD) has entered the "golden age" of drug development. Until now, the landscape was comprised of 3 major mechanistic classes: (1) corticosteroids, calcineurin…
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Jan 31
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FULL SUPPLEMENT: Masterful Topical JAK Inhibitor

By Chuck Lin No Comments
In this issue:VEHICLES MATTER: DESIGNED FOR PURPOSEThere are several oral JAK formulations available in the United States market. The first topical cream formulation of a JAK inhibitor is ruxolitinib cream…
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Jan 31
Love0

INDIVIDUAL ARTICLE: Etiology, Treatment Challenges, and the Role of Scalp and Haircare in Managing Dandruff

By Chuck Lin No Comments
INTRODUCTIONDandruff and seborrheic dermatitis (D/SD) affect about half of the general population worldwide.1 SD in the scalp is commonly known as dandruff and is considered the same condition with varying…
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Jan 31
Love0

INDIVIDUAL ARTICLE: VEHICLES MATTER: DESIGNED FOR PURPOSE

By Chuck Lin No Comments
Janus kinase (JAK) inhibitors, which have been used in a range of disease states from rheumatology to gastroenterology, have been finally adopted into dermatology. These agents are rapidly changing the…
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Jan 31
Love0

A Multi-Component Reaction Peptide Augmenting the Anti-Aging Benefits of Non-Ablative Laser Procedure

By Chuck Lin No Comments
INTRODUCTIONLaser resurfacing has been the gold standard for the rejuvenation of photodamaged skin over the past four decades.1-4 Ablative laser procedures can efficiently address signs of aging by vaporizing the…
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Jan 31
Love0

FULL SUPPLEMENT: Scalp Health & the Role of the Scalp Barrier in Dandruff and Seborrheic Dermatitis

By Chuck Lin No Comments
In this issue:Insights on the Impact of Scalp Barrier Condition on Hair HealthScalp health is essential for healthy hair growth and may be affected by intrinsic or extrinsic factors. Reactive…
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Jan 31
Love0

INDIVIDUAL ARTICLE: Ruxolitinib 1.5% Cream and the “Boxed Warning Paradox”: Reappraisal of Safety Through the Lens of Pharmacokinetics

By Chuck Lin No Comments
INTRODUCTIONJanus kinase (JAK) proteins are key, evolutionarily conserved mediators of external-to-internal cellular signaling, activated when external cytokines bind to their respective transmembrane receptors, triggering phosphorylation of JAK proteins, then STAT…
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Jan 30
Love0

Guselkumab Efficacy by Psoriasis Disease Severity and Treatment History: VOYAGE 1 and 2 Post Hoc Analyses

By Chuck Lin No Comments
INTRODUCTIONPsoriasis is a chronic, systemic, immune-mediated, inflammatory disease that often negatively affects physical and emotional health-related quality of life.1,2 Current guidelines for the treatment of moderate-to-severe plaque psoriasis recommend the…
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Jan 30
Love0

Visual Assessment Tools and Therapeutic Implications for Acanthosis Nigricans

By Chuck Lin No Comments
INTRODUCTIONAcanthosis nigricans (AN) is a common skin condition marked by hyperpigmented, velvety plaques.1 In the United States, AN has a prevalence of 19.4%2 and disproportionately impacts individuals with skin of…
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Jan 30
Love0

Dupilumab Treatment Improves Lichenification in Atopic Dermatitis in Different Age and Racial Groups

By Chuck Lin No Comments
INTRODUCTIONLichenification, associated with disease chronicity in moderate to severe atopic dermatitis (AD), is a skin sign characterized by skin thickening with demarcated skin lines and leathery aspect, partially resulting from…
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Jan 29
Love0

Non-Surgical Correction of Dermatochalasis Using Microplasma

By Chuck Lin No Comments
INTRODUCTIONDermatochalasis (DC) refers to the redundancy of upper eyelid skin formed during the aging process. The upper eyelid skin is the thinnest in the body and contains minimal subcutaneous fat,…
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