INTRODUCTIONDermatology providers have traditionally used a test dose (TD) of methotrexate when initiating treatment to assess a patient's predisposition to severe adverse events, particularly myelosuppression.1 Although not standardized, a TD…
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INTRODUCTIONFlap Design and Movement When linear closure along the resting skin tension lines (RSTL) is inappropriate for a given defect, other repairs may be considered. Rotation flaps can be a…
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In this issue:VEHICLES MATTERAlthough data suggest that antibiotic use by dermatologists is decreasing, our specialty still has the highest rates of oral antibiotic prescribing across all fields of medicine.1,2 In…
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Although data suggest that antibiotic use by dermatologists is decreasing, our specialty still has the highest rates of oral antibiotic prescribing across all fields of medicine.1,2 In an era of…
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INTRODUCTIONAntibiotics are among the most frequently prescribed medications in clinical medicine and have long been central to dermatologic practice, particularly for the management of chronic inflammatory conditions such as acne…
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INTRODUCTIONAtherosclerotic cardiovascular disease (ASCVD) is the leading cause of morbidity and mortality worldwide and demands early identification and tailored risk reduction strategies.1 Randomized controlled trials have established the efficacy of…
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INTRODUCTIONRoflumilast is a topical phosphodiesterase-4 inhibitor (PDE-4i) approved by the Food and Drug Administration (FDA) for treating dermatological conditions, including plaque psoriasis and atopic dermatitis. The 0.15% formulation was approved…
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INTRODUCTIONMohs micrographic surgery (MMS) has emerged as a highly effective and precise treatment for skin cancer, offering exceptional cure rates while preserving healthy tissue.1 MMS involves the sequential removal of…
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INTRODUCTIONSun exposure is a risk factor for melanoma and non-melanoma skin cancer (NMSC),1,2 with NMSC being the cause of most skin cancer-related deaths.3 In addition, sun exposure contributes to photoaging,…
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INTRODUCTIONHair loss is a common dermatologic condition associated with significant psychosocial distress.1 It has been estimated that 50% of men and women suffer from the most common form of hair…
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INTRODUCTIONNicotinamide, also known as niacinamide, represents the water-soluble form of vitamin B3, while niacin, or nicotinic acid, constitutes its acidic counterpart. Nicotinamide plays a crucial role in our bodies by…
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CASE REPORTA 66-year-old woman with vulvar lichen sclerosis, Raynaud's phenomenon, and biliary colic status-post cholecystectomy presented for an intensely pruritic rash ongoing for several months. The eruption affected her right…
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