INTRODUCTIONCicatricial pemphigoid (CP) is a chronic, subepidermal blistering disease of autoimmune origin.1 Brunsting-Perry cicatricial pemphigoid is a rare localized variant of CP characterized by a pruritic vesiculobullous eruption that predominately…
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INTRODUCTIONWhile the majority of patients are helped by current dermatologic therapy, there are a number of patients who find no relief, or are afraid of the side effects of powerful…
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INTRODUCTIONPsoriasis is a chronic dermatologic disease that affects more than 7.4 million individuals in the United States (US).1 Biologic therapies targeting inflammatory cytokines have become an important treatment option for…
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INTRODUCTIONIncobotulinumtoxinA (INCO; Xeomin®, Bocouture®; Merz Pharmaceuticals GmbH, Frankfurt am Main, Germany) is approved in the United States and worldwide markets for treating glabellar frown lines (GFL) at a dose of…
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INTRODUCTIONWhen looking at the history of using electricity to stimulate muscles (ie, electric muscle stimulation or electrostimulation), as with many other new medical and scientific concepts, we can infer there…
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In this supplement:Safety and Tolerability of Topical Agents for Actinic Keratosis: A Systematic Review of Phase 3 Clinical TrialsTopical agents for actinic keratosis (AK), along with cryotherapy and phototherapy, are…
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Actinic keratoses (AK) are among the most common dermatologic presentations, with estimates suggesting that they account for approximately 15 percent of dermatologic diagnoses in the US.1 Incidence of AK increases…
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INTRODUCTIONActinic keratoses (AKs) are hyperkeratotic, erythematous papules or plaques with overlying scale and rough texture found in sun-damaged areas of skin.1 They represent a chronic and recurring manifestation of field…
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INTRODUCTIONHidradenitis suppurativa (HS) is an inflammatory, debilitating, skin follicular disease that usually presents after puberty with painful, deep-seated, inflamed lesions in the apocrine gland-bearing areas of the body, most commonly…
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INTRODUCTIONUnderstanding of the immunologic basis of chronic plaque psoriasis has led to the development of several classes of biological agents, primarily monoclonal antibodies, including inhibitors of tumor necrosis factor (TNF),…
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Immune checkpoint inhibitors (ICPis) have revolutionized outcomes in various advanced malignancies. Therapeutic restoration of a robust T-cell response against malignant cells is also at the root of distinct cutaneous immune-related…
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With all the literature and research we have on acne and rosacea, there are still many unanswered questions. Over time, as we uncover more information on both preexisting and newly…
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