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Dec 10
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Vismodegib as Eye-Sparing Neoadjuvant Treatment for Locally Advanced Periocular Basal Cell Carcinoma

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INTRODUCTIONLocally-advanced basal cell carcinoma (BCC) often pose considerable therapeutic challenges because of the need to preserve functionality and cosmesis of the affected region.1 In high-risk, aggressive or recurrent tumors of…
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Dec 10
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Novel Treatment of In-Transit Metastatic Melanoma With Shave Excision, Electrodesiccation and Curettage, and Topical Imiquimod 5% Cream

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INTRODUCTIONIn-transit metastatic melanoma (ITMM) is defined as metastases of melanocytes within the regional dermal or subcutaneous lymphatics greater than 2 cm from the primary lesion but not further than regional…
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Dec 10
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Bilateral Contiguous Scrotal Extramammary Paget’s Disease Treated With Mohs Micrographic Surgery and CK7 Immunohistochemical Staining

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INTRODUCTIONExtramammary Paget’s Disease (EMPD) is a rare malignancy that commonly presents on apocrine-rich skin as a unilateral scaly patch or plaque that often grows slowly and asymmetrically.1 There is growing…
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Dec 10
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The Effect on BSA of Proactive Management versus Reactive Management of Psoriasis With Fixed-Dose Cal/BD Foam in the PSO-LONG Study

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INTRODUCTIONArecent Phase III clinical study (PSO-LONG, NCT02899962) assessed the benefit of proactive management of psoriasis using twice-weekly calcipotriene/betamethasone dipropionate (Cal/BD) foam in patients successfully treated with once-daily Cal/BD foam. Patients…
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Dec 10
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Anatomical Definition of the Target Structures of a Jet-Based Tissue Penetration

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INTRODUCTIONJet injection provides an intradermal drug delivery through invasive but needle-free route of administration. The modality implements a pressurized stream of liquid that penetrates the skin with a minimal injury…
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Dec 10
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Bovine Colostrum, Telomeres, and Skin Aging

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INTRODUCTIONAs skin ages, fine lines, deep wrinkles, dryness, and uneven texture begin to appear. Sun exposure, pollution, and unhealthy lifestyle choices result in chronic inflammation, degradation of collagen, and other…
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Dec 10
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Basal Cell Carcinoma Gene Mutations Differ Between Asian, Hispanic, and Caucasian Patients: A Pilot Study

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INTRODUCTIONBasal cell carcinoma (BCC) is the most common malignancy in the United States with approximately 4.3 million cases each year.1-3 Nonmelanoma skin cancer, 80% of which are BCC, compose more…
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Dec 10
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Comparative Evaluation of Efficacy and Safety of Tacrolimus and Dinoprostone Following Dermabrasion in Stable Vitiligo

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INTRODUCTIONVitiligo is a disorder of skin color characterized by defective melanocyte proliferation and melanosome transfer with an unpredictable course. With a dearth of therapeutic options, the present study assesses the…
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Dec 10
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Comparative Study of Intralesional Vitamin D3 Injection and Candida Albicans Antigen in Treating Plantar Warts

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INTRODUCTIONMany treatment methods exist for treating plantar warts, yet high rates of treatment failure are reported and no one single treatment is regarded optimal for curing the condition. Up to…
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Dec 10
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FULL SUPPLEMENT: Integrating Gene Expression Profiling into the Management of Cutaneous Squamous Cell Carcinoma

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In this supplement: Bridging the Gap: Integrating Gene Expression Profiling into Clinical PracticeClinicians who treat patients with cutaneous squamous cell carcinoma (CSCC) face a unique set of management challenges. While…
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Dec 10
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Bridging the Gap: Integrating Gene Expression Profiling into Clinical Practice

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Clinicians who treat patients with cutaneous squamous cell carcinoma (CSCC) face a unique set of management challenges. While the aim is to identify biologically aggressive tumors at earlier stages of…
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Dec 10
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Clinical Considerations for Integrating Gene Expression Profiling into Cutaneous Squamous Cell Carcinoma Management

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INTRODUCTIONAs the population of the United States continues to grow and age, the number of patients being diagnosed with nonmelanoma skin cancer (NMSC) is also changing. From 2006 to 2012,…
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