INTRODUCTIONOrganization and Function of Epidermis Providing an Efficient Skin Barrier The epidermis maintains its homeostasis and serves critical functions through a dynamic, self-renewing process in which the basal keratinocytes divide…
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INTRODUCTIONThe human skin is critical in protecting internal organs from exogenous factors to maintain homeostasis by contributing to a multifaceted structure known as the skin barrier. The stratum corneum (SC),…
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INTRODUCTION“A pivotal point of terrestrial adaptation is prevention of desiccation and maintenance of internal water homeostasisâ€.1 The critical role of the stratum corneum (SC) permeability barrier is the protection of…
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INTRODUCTIONThe human skin barrier is a complex structure comprising of physical, chemical, immunological, and microbial components that maintain skin homeostasis whilst protecting the body from external irritants.1 The outermost layer…
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ARTICLE: Efficacy of Ceramide-Containing Formulations on UV-Induced Skin Surface Barrier Alterations
INTRODUCTIONThe epidermis, the skin’s outermost layer, functions as a barrier against environmental aggressors through the cornification of keratinocytes to form the stratum corneum (SC). Embedded within a lipid matrix that…
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Cutaneous Lichen Planus affects 0.2–1% of adults worldwide, primarily between 30–60, with a 3:2 female predominance. Despite an association with HCV, and a possible role for contact allergens, pathogenesis remains…
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INTRODUCTIONFacial palsy is a common problem from which many patients do not completely recover and hence have to live with chronic sequelae.1 These may include discomfort, functional deficiencies, and aesthetic…
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INTRODUCTIONMore than 1 billion US dollars were spent in 2018 on treatments with injectable agents like neuromodulators or soft tissue fillers for aesthetic purposes according to the annual statistic report…
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INTRODUCTIONDyshidrotic eczema, also known as dyshidrosis or pompholyx when involving larger bullae, is a chronic, relapsing palmoplantar dermatosis characterized by intensely pruritic and frequently painful deep-seated vesicles and bullae. Often…
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INTRODUCTIONBlastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive malignancy caused by transformed plasmacytoid dendritic cells that overexpress interleukin-3 receptor subunit alpha (IL3RA) also known as CD123.1 Tagraxofusp-erzs…
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In this supplement:Efficacy of Ceramide-Containing Formulations on UV-Induced Skin Surface Barrier Alterations The human skin, particularly the stratum corneum, serves as a protective barrier against exogenous factors, including ultraviolet radiation…
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INTRODUCTIONThe use of dermal fillers is the second most prevalent, minimally invasive aesthetic procedure performed in the United States, reaching 2.6 million in 2018.1 Among the available dermal fillers, calcium…
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