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Dec 10
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Afamelanotide: An Orphan Drug with Potential for Broad Dermatologic Applications

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INTRODUCTIONAfamelanotide (SCENESSE®) is a synthetic analogue of α‐melanocyte‐stimulating hormone (α-MSH) that induces tanning of the skin. α-MSH is a product of the proopiomelanocortin gene (POMC), which is cleaved into the…
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Dec 10
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Adding Combined Oral Contraceptives or Metformin to Laser Treatment in Polycystic Ovarian Syndrome Hirsute Patients

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INTRODUCTIONHirsutism is defined as the growth of excessive terminal hair in androgen-dependent sites in females.1 Hirsutism affects 10% to 20% of women,2 having a major impact on their quality of…
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Dec 10
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The Use of Tranexamic Acid to Prevent and Treat Post-Inflammatory Hyperpigmentation

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CASE 1A 38-year-old woman with Fitzpatrick skin type 3 complained of a burning 20 minutes after the application of topical anesthetic cream: benzocaine 20%, lidocaine 8%, and tetracaine 4% (BTL…
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Dec 10
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Novel Facial Treatment Regimen Improves Aging Skin Appearance

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INTRODUCTIONThe clinical appearance of aging skin is the result of natural aging superimposed with the effects of the environment or extrinsic aging. While solar radiation remains the most important factor…
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Dec 10
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A Clinical Study Evaluating the Efficacy of Topical Bakuchiol (UP256) Cream on Facial Acne

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INTRODUCTIONAcne vulgaris, or acne, is a common skin condition that affects approximately 10% of the global population.1 Despite their efficacy, many acne medications are irritating, decreasing adherence to therapy. Treatment-related…
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Dec 10
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Coronavirus Vaccination Adverse Reactions and the Role of the Dermatologist

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A nationwide vaccination program against coronavirus disease 2019 (COVID-19) has materialized as Emergency Use Authorizations (EUA) have been issued for the Pfizer-BioNTech and Moderna COVID-19 vaccines. These vaccines rely on…
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Dec 10
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Successful Treatment of Infraorbital Occlusion With the High-Dose Pulsed Hyaluronidase Protocol: A Case Report and Literature Review

By No Comments
INTRODUCTIONFacial fillers are an increasingly popular cosmetic procedure used for facial rejuvenation. Regardless of the experience and skill level of the injector, fillers can inadvertently occlude vessels leading to blockage…
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Dec 10
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Mohs Micrographic Surgery for Genital Skin Cancer: A Review of Cases and Reconstructive Techniques

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INTRODUCTIONSkin cancer is the most common form of cancer in the United States, and the incidence has risen drastically in the last decade. From 2006 to 2012 alone, the annual…
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Dec 10
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Once-Daily Halobetasol Propionate 0.01% Lotion for Moderate-to-Severe Plaque Psoriasis: Phase 3 Analysis of Hispanic Participants

By No Comments
INTRODUCTIONPsoriasis is a chronic, inflammatory immune-mediated disease that occurs throughout the world.1 Although dermatologic disorders are common in all racial and ethnic groups,2 clinical data on psoriasis in skin of…
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Dec 10
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Successful Treatment of Lichen Amyloidosis Using a Fixed Combination of Halobetasol-Propionate and Tazarotene Lotion

By No Comments
INTRODUCTIONLichen amyloidosis is characterized by “rippled”, brown, extremely pruritic plaques, typically on the lower extremities, that is often refractory to medical intervention. Here, a case of lichen amyloidosis successfully treated…
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Dec 10
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A Retrospective Review of Patients’ Response to Biologic Therapy for Psoriasis

By No Comments
INTRODUCTIONPsoriasis is a lifelong, relapsing, immune-mediated disease that primarily affects the skin and joints.1-3 It is estimated to affect more than 7 million people in the Unites States and approximately…
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Dec 10
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Methotrexate Monitoring in Dermatology— A Retrospective Cohort Study

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INTRODUCTIONMethotrexate (MTX) is an immunosuppressive medication used to treat a wide range of dermatological conditions, most commonly psoriasis.1 MTX was first approved by the Food and Drug Administration (FDA) in…
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