The Microsponge Delivery System (MDS) for Tretinoin: A First Attempt at Reducing IrritationThe Microsponge Delivery System (MDS) is a controlled drug delivery system that encapsulates the active drug, releasing it…
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Tretinoin Formulation: From Microsponges to Polymeric EmulsionThe history of tretinoin and its use in dermatology is a testament both to the drug’s well-established efficacy and its potential to cause skin…
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INTRODUCTIONThe pathogenesis of acne is attributed to a combination of changes in the skin. Many of these changes are dominantly regulated by the sebaceous gland and include increased sebum production,…
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INTRODUCTIONThe latest 2010 United States Census indicates that 2.9 million people identify as Native American (NA). Forty-one percent live in the Western states (Arizona, California, Colorado, Montana, Nevada, New Mexico,…
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INTRODUCTIONThe ability of microfocused ultrasound (MFU) to create discrete thermal injury zones within the facial superficial musculoaponeurotic system (SMAS) and denature collagen to induce shrinkage and tissue tightening was demonstrated…
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Hidradenitis suppurativa (HS) is a relapsing, inflammatory skin disease characterized by painful nodules, abscesses, fistulae, and scarring. HS has a great impact on patients’quality of life and its treatment may…
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INTRODUCTIONUpper eyelid blepharoplasty, one of the most common plastic surgery procedures performed, involves surgically excising excess upper eyelid skin to provide an aesthetically rejuvenated appearance to the periorbital area.1,2 In…
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INTRODUCTIONIt is well known ultraviolet (UV) light and DNA damage can lead to skin cancer. This occurs when epidermal keratinocytes are exposed to UV radiation, forming dimers and oxygen radicals…
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INTRODUCTIONPrimary cutaneous anaplastic large cell lymphoma (pc-ALCL) is a CD30+ subtype of cutaneous T-cell lymphoma (CTCL). It typically presents as one or more nodules on the skin with a dermal…
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INTRODUCTIONLeiomyomas are benign neoplasms derived from smooth muscle and are primarily found in the gastrointestinal and female genital tract. In the skin, leiomyomas present as dermal-based nodules or papules with…
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INTRODUCTIONSorafenib is an antineoplastic agent that acts through inhibition of C-RAF and B-RAF kinases, vascular endothelial growth factor (VEGF), and platelet-derived growth factor receptor (PDGF).1 Sorafenib has been approved by…
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BACKGROUNDReflectance Confocal Microscopy (RCM) is a new tool in the diagnosis and monitoring of skin disease. RCM uses an 830 nm laser to illuminate the skin and captures horizontal cross-sectional…
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