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Dec 10
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Superficial Radiation Therapy: A Viable Nonsurgical Option for Treating Basal and Squamous Cell Carcinoma of the Lower Extremities

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INTRODUCTIONNonmelanoma skin cancer (NMSC), consisting primarily of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), represents the most commonly encountered type of cancer. As advanced age is a significant…
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Dec 10
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Histopathology of Basal Cell Carcinoma After Treatment With Vismogedib

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INTRODUCTIONNon-melanoma skin cancer (NMSC) is the most common cancer, with basal cell carcinoma (BCC) as the most prevalent subtype. It is estimated that there were more than 5.4 million incident…
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Dec 10
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Natural Skin Care Products as Adjunctive to Prescription Therapy in Moderate to Severe Rosacea

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INTRODUCTIONRosacea is a challenging dermatological condition due to its multifactorial causes.1 Diet, environment, menopause, mites, bacteria, cathelicidins, and improper skin care have all been implicated as contributing causes of the…
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Dec 10
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Is It Time to Rethink What Thickness Really Means as a Prognostic Indicator in Melanoma? Ten Questions We Should Be Asking Ourselves

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INTRODUCTION1. Why question the value of tumor thickness as a prognostic indicator for melanoma?Since Dr. Clark’s observations in the 1960’s, it has been well-accepted that melanoma thickness is a very…
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Dec 10
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The Efficacy of Topical Minoxidil for Non-Scarring Alopecia: A Systematic Review

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INTRODUCTIONMinoxidil (MXD) is a potent vasodilator and oral antihypertensive agent that was discovered to induce hypertrichosis in 60-80% of patients. Exploitation of MXD’s hypertrichosis effect led to the development of…
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Dec 10
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A Review of the Dermatologic Symptoms of Idiopathic Mast Cell Activation Syndrome

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INTRODUCTIONMast cells (MCs) are derived from a hematopoietic origin and are found in all human tissues. Upon activation by either immunologic or non-immunologic mechanisms, the former of which involves an…
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Dec 10
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Apremilast for the Treatment of Mild-to-Moderate Hidradenitis Suppurativa in a Prospective, Open-Label, Phase 2 Study

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INTRODUCTIONHidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory skin disease of the hair follicle1 that affects nearly 1% of the general population.1-3 This rare condition is most common in adults…
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Dec 10
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Novel Tretinoin 0.05% Lotion for the Once-daily Treatment of Moderate-to-Severe Acne Vulgaris in an Adult and Adolescent Female Population

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INTRODUCTIONAlthough acne vulgaris (acne) is principally a disorder of adolescence, research suggests the prevalence of adult acne is increasing, especially in females.1,2 The most common type of acne seen in…
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Dec 10
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Tavaborole 5% Topical Solution for the Treatment of Toenail Onychomycosis in Pediatric Patients: Results from a Phase 4 Open-Label Study

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INTRODUCTIONThe estimated prevalence of onychomycosis among the adult population in Europe and North America is 4.3%.1 Although prevalence is lower among pediatric patients,2,3 the burden of disease with onychomycosis is…
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Dec 10
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Cortexolone 17α-Propionate (Clascoterone) is an Androgen Receptor Antagonist in Dermal Papilla Cells In Vitro

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Dec 10
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Applications of Topical Oak Bark Extract in Dermatology: Clinical Examples and Discussion

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INTRODUCTIONAs concerns for antibiotic resistance lead to calls for stewardship, and negative perceptions of steroids by patients influence treatment options, there is a growing interest in "natural" or alternative approaches…
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Dec 10
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Pustular DRESS Syndrome Secondary to Hydroxychloroquine With EBV Reactivation

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INTRODUCTIONDrug reaction with eosinophilia and systemic symptoms (DRESS), or drug-induced hypersensitivity syndrome (DIHS), is a potentially life-threatening adverse medication effect with mortality rates up to 10 percent.1,2 Most often, it…
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