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Dec 10
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A Prospective, Open-Label Study Evaluating Adjunctive Calcipotriene 0.005%/Betamethasone Dipropionate 0.064% Foam in Psoriasis Patients With Inadequate Response to Biologic Therapy

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INTRODUCTIONPsoriasis is a chronic inflammatory skin disease that affects as many as 7.4 million adults in the United States.1,2 It is characterized by disfiguring, scaling, erythematous plaques that can be…
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Dec 10
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Safety and Efficacy of a Fixed Combination Halobetasol and Tazarotene Lotion in the Treatment of Moderate-to-Severe Plaque Psoriasis: A Pooled Analysis of Two Phase 3 Studies

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INTRODUCTIONPsoriasis is a chronic, immune-mediated disease affecting almost 2% of the population.1-3 Topical therapy is a key component in the management of almost all psoriasis patients, considered first-line therapy for…
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Dec 10
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Rapid Onset of Action in Patients With Moderate-to-Severe Plaque Psoriasis With Halobetasol 0.01%/Tazarotene 0.045% Fixed Combination

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INTRODUCTIONPsoriasis is a chronic disease that has a substantial effect on quality of life (QoL), and the psychosocial disability suffered by psoriasis patients highlights the need for prompt, effective, and…
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Dec 10
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Efficacy and Safety of Toreforant, a Selective Histamine H4 Receptor Antagonist, for the Treatment of Moderate-to-Severe Plaque Psoriasis: Results from a Phase 2 Multicenter, Randomized, Double-blind, Placebo-controlled Trial

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INTRODUCTIONOrally administered psoriasis therapies that can provide high levels of efficacy, safety, and tolerability remain an unmet need. Toreforant is an orally bioavailable, novel, and selective histamine H4 receptor (H4R)…
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Dec 10
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Patient-Reported Satisfaction With the Fixed Combination Calcipotriene/Betamethasone Dipropionate Foam for Plaque Psoriasis

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INTRODUCTIONPsoriasis is a chronic, immune-mediated inflammatory disease that affects >3% of adults aged ≥20 years in the United States.1,2 Primarily characterized by localized scaling and plaques that can cause itching…
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Dec 10
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Discordance Between Patient Reported Motivations to Seek Treatment for Psoriasis Compared to Television Advertisements

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INTRODUCTIONPharmaceutical companies spend billions of dollars yearly advertising medications. Spending on direct to consumer advertisements for psoriasis agents in particular has increased considerably over the last several year. Four of…
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Dec 10
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A Phase 2, Controlled, Dose-Ranging Study of SB208, an Investigational Topical Nitric Oxide-Releasing Drug, for the Treatment of Tinea Pedis

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INTRODUCTIONThe incidence of mycologic diseases is rising, due to the increased use of communal recreational facilities, as well as the increased incidence of individuals who are immunocompromised.1 Tinea pedis, also…
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Dec 10
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A Novel, Optimized Method to Accelerate the Preparation of Injectable Poly-L-Lactic Acid by Sonication

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INTRODUCTIONPoly-L-lactic acid (PLLA; Sculptra®, Galderma, Fort Worth, TX) injection is an effective treatment option for correction of bony and soft tissue facial deficiencies.1 PLLA, as synthetic polymer derivative from the…
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Dec 10
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Cosmetic Versus Medicine: How Does Your Country Define Sunscreen?

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INTRODUCTIONSkin cancer (melanoma and non-melanoma) is the most commonly diagnosed cancer in the United States,1,2 with melanoma being responsible for over 9000 US deaths annually. Melanoma is the 3rd most…
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Dec 10
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UV Protection by Natural Products: C. myrrha Oil Versus Sunscreen

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INTRODUCTIONThe link between exposure to solar ultraviolet (UV) radiation and cancer incidence is well-established.1,2 Interventions to promote the use of protection against UV radiation, such as the use of sunscreen,…
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Dec 10
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Evaluation of the Performance of a Nature-Based Sensitive Skin Regimen in Subjects With Clinically Diagnosed Sensitive Skin

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INTRODUCTIONSensitive skin is a syndrome of unpleasant sensations (stinging, burning, pain, pruritus, and tingling sensations) in response to stimuli that normally do not provoke such sensations.1-3 Subjective complaints of discomfort…
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Dec 10
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An Excellent Response to Tofacitinib in a Pediatric Alopecia Patient: A Case Report and Review

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DISCUSSIONAlopecia areata (AA) is an autoimmune disorder characterized by the sudden onset of non-scarring hair loss in a patch distribution.1 The hair loss can occur in any hair bearing area,…
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