INTRODUCTION Laser removal of dark hair can be accomplished with a variety of melanin absorbing chromophore wavelengths. Such light systems include 694-1064 nm laser systems.1 Laser hair removal of blond…

INTRODUCTIONMelasma is a cutaneous pigmentation condition affecting predominantly women. It is a highly prevalent condition observed by dermatologists,1 as it is a chronic disorder to which the therapeutic response is…

INTRODUCTIONPrimary focal axillary hyperhidrosis is a chronic disorder presenting as excessive underarm sweating. Multiple studies have established the psychosocial burden of primary hyperhidrosis and its negative impact on quality of…

INTRODUCTIONAcne vulgaris affects 40 to 50 million people in the United States and is the most common skin disease treated by physicians.1-3 Peak incidence occurs during adolescence, affecting approximately 85%…

INTRODUCTION Topical tretinoin (all-trans-retinoic acid), a first-line therapy for acne vulgaris treatment, is recommended as maintenance therapy for acne, primarily due to its ability to reduce comedone formation without inducing…

INTRODUCTION AND CLINICAL OVERVIEWPeriorbital Hyperpigmentation (POH) is also known by the following names: periorbital melanosis, periorbital circles, dark circles, dark eye circle, underye circles, perioccular pigmentation, perioccular melanosis, infraorbital melanosis,…

INTRODUCTION Melasma is an acquired hypermelanosis that typically affects sun-exposed areas on the face and presents as symmetric brownish macules and patches coalescing in a reticular pattern.1 An estimated 6…

CASE REPORTAn eight year-old Hispanic female with a history of pre-B cell acute lymphoblastic leukemia presented to our clinic due to excessive hair on her face and arms for 16…

CASE REPORT A new generation of anticancer pharmaceuticals designed to inhibit specific malignancy-associated enzymes has become available in recent years. Vemurafenib represents one such medication and targets the V600E-substituted B-Raf…

Mayo Clinic Jacksonville opened in 1986 on the intracoastal waterway of Florida just miles from Jacksonville Beach, and was the first Mayo Clinic campus outside of Rochester, MN. Initially staffed…

DISCLOSURES The authors have not disclosed any relevant conflicts of interest.AUTHOR CORRESPONDENCEJason C. Sluzevich MDSluzevich.jason@mayo.edu

CASE A 51-year-old African American female presented with a 4-month history of progressive skin ulcers on the lower extremities, associated with severe and unrelenting paresthetic pain that preceded the skin…