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Dec 10
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Response to the Possibility of the Application of Topical Photodynamic Therapy Leading to Development of More Histologically Aggressive Subtypes of Basal Cell Carcinomas

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The incidence of non-melanoma skin cancers (NMSCs) has been dramatically increasing, with basal cell carcinomas (BCCs) accounting for about 80% of the tumors.1 In the last decade, huge efforts have…
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Dec 10
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Essential Factors Influencing Health-Related-Quality of Life in Psoriasis

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INTRODUCTION The impairment of the health related quality of life (HRQoL) caused by psoriasis can be compared to other severe diseases such as ischemic heart disease, chronic obstructive pulmonary disease,…
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Dec 10
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Efficacy of Tofacitinib, an Oral Janus Kinase Inhibitor, on Clinical Signs of Moderate-to-Severe Plaque Psoriasis in Different Body Regions

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INTRODUCTIONPsoriasis is a common, lifelong, immune-mediated genetic disease, resulting in a substantial physical and emotional burden. In psoriasis, an activated cytokine network stimulates a cycle of ongoing inflammation and cellular…
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Dec 10
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Topical Clofibrate Improves Symptoms in Patients With Atopic Dermatitis and Reduces Serum TARC Levels: A Randomized, Double-Blind, Placebo-Controlled Pilot Study

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INTRODUCTIONTopical corticosteroids (TC) are commonly regarded as a mainstay of AD therapy. However, there exist several problems including topical steroid addiction (TSA) or Red burning skin syndrome.1,2 There are a…
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Dec 10
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Assessment of Hypoallergenicity of Ten Skincare Products

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INTRODUCTIONDespite its ubiquity, a single definition for “sensitive skin” remains elusive and there is little agreement among dermatologists beyond heightened sensitivity on its symptomatology.1 Most of the research data currently…
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Dec 10
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Use of Ingenol Mebutate Gel for Actinic Keratosis in Patients in a Community Dermatology Practice

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INTRODUCTION Patients with heavily sun-damaged skin frequently have a substantial burden of actinic keratosis (AK) and subclinical AKs that are commonly treated with topical therapy to target large areas. Although…
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Dec 10
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From DNA Repair to Proteome Protection: New Molecular Insights for Preventing Non-Melanoma Skin Cancers and Skin Aging

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INTRODUCTIONNon-melanoma skin cancers (NMSC) are the most common cancer worldwide and pose a significant and increasing burden on health care resources, with an estimated cost of $650 million and 2,200…
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Dec 10
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In Vivo Efficacy of Nano Hyaluronan-Conjugated Cisplatin for Treatment of Murine Melanoma

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INTRODUCTIONMelanoma is a deadly skin cancer, killing more than 9,000 Americans in 2012. Incidence is rising rapidly, to the point where 1 in 50 Americans will develop melanoma.1 Stage at…
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Dec 10
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The “Smile-and-Fill” Injection Technique: A Dynamic Approach to Midface Volumization

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INTRODUCTIONInjectable poly-L-lactic acid (PLLA) is a biodegradable, biocompatible, synthetic polymer that acts as a scaffold to promote collagen formation.1 It is FDA-approved for the correction of facial lipoatrophy in patients…
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Dec 10
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Selective Radiofrequency Therapy as a Non-Invasive Approach for Contactless Body Contouring and Circumferential Reduction

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INTRODUCTIONExcessive fat is not only cosmetic but also an overall health problem. People who exceed their ideal body weight by more than 20% have an increased risk of type 2…
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Dec 10
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A Preliminary Study on the Safety and Efficacy of a Novel Fractional CO2 Laser With Synchronous Radiofrequency Delivery

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INTRODUCTION AND BACKGROUNDCarbon dioxide (CO2) laser skin resurfacing has been the “gold standard” for cutaneous facial resurfacing of photo-damaged skin since its emergence in the marketplace in the mid-1990s.1-4 Fully…
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Dec 10
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Thanaka: Traditional Burmese Sun Protection

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INTRODUCTION Limonia acidissima or Hesperethusa crenulata is a common tree in Southeast Asia. It is indigenous to the Republic of Myanmar (formerly Burma) as well as India, Sri Lanka, Java,…
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