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Dec 10
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Undesirable Effects After Treatment With Dermal Fillers

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INTRODUCTION Dermal fillers have been used to improve the loss of facial volume for more than 20 years, although with the new products, this cosmetic procedure has undergone significant development…
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Dec 10
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The Therapeutic Effects of a Topical Tretinoin and Corticosteroid Combination for Vitiligo: A Placebo-Controlled, Paired-Comparison, Left-Right Study

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INTRODUCTIONTopical corticosteroids are commonly used for the treatment of vitiligo. The slow repigmentation with treatment and the recurrent loss of pigmentation usually requires long-term use of topical steroids, which frequently…
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Dec 10
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The Therapeutic Role of Isotretinoin in the Management of Behçet’s Disease: A Single-Blinded, Controlled Therapeutic Study

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INTRODUCTION Behçet’s disease (BD) is relatively common in many countries, including Iraq.1 Its etiopathogenesis is not well elucidated, but many factors have been incriminated, such as genetic predisposition, infectious agents,…
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Dec 10
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Molecular Skin Research Can Impact Systemic Cancers

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This issue of JDD is dedicated to skin cancer and is a harbinger of major contributions of skin research to the exploding knowledge of targeted therapy and immunotherapy of cancers.…
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Dec 10
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Periungual Pyogenic Granuloma Following Imatinib Therapy in a Patient With Chronic Myelogenous Leukemia

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A 51-year-old woman presented to our attention because of a rapidly growing and painful toenail lesion. The lesion had been present for a few weeks.The patient was affected by Philadelphia…
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Dec 10
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Comorbidities Associated With Leptin and Psoriasis

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The recent article by Aly et al provided for highly stimulating and interesting reading.1 Elevated serum leptin in patients with psoriasis may contribute to the development and progression of a…
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Dec 10
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Cosmeceuticals for Recurrence Prevention After Prior Skin Cancer: An Overview

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INTRODUCTIONSkin cancer is the most common form of cancer in the United States. According to the World Health Organization, the incidence of both nonmelanoma and melanoma skin cancers has increased…
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Dec 10
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Targeting the Hedgehog Pathway to Treat Basal Cell Carcinoma

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INTRODUCTIONBasal cell carcinoma (BCC) is the most common malignancy in people of European descent.1,2 BCCs comprise approximately 80% of nonmelanoma skin cancers. In the United States, more than 2 million…
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Dec 10
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Nontraditional Management of Basal Cell Carcinoma

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BACKGROUND Skin cancer is increasing at epidemic proportions in the United States. More than 3.5 million nonmelanoma skin cancers (NMSCs)1 are diagnosed in the United States annually, with basal cell…
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Dec 10
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Treatment of Facial Photodamage Using a Novel Retinol Formulation

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INTRODUCTIONRepeated exposure to solar ultraviolet (UV) radiation causes human skin to age prematurely (photoaging).1,2 Photoaged skin is characterized by a variety of clinical, histologic, and biochemical features. Wrinkles, uneven pigmentation…
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Dec 10
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The Clinical Effects of Zinc as a Topical or Oral Agent on the Clinical Response and Pathophysiologic Mechanisms of Acne: A Systematic Review of the Literature

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INTRODUCTION Acne vulgaris is a common, multifactorial disease characterized by 4 pathophysiologic processes: 1) presence and activity of bacteria, 2) inflammation, 3) excess sebum production, and 4) excess keratinization.1 Clinically,…
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Dec 10
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Combination Therapy for Psoriasis in the United States

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INTRODUCTION Psoriasis patients are often frustrated with the treatment they receive.1-3 The quality-of-life impact of psoriasis is comparable to that of other major medical diseases such as arthritis, hypertension, and…
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