INTRODUCTION Acne vulgaris is one of the most common dermatologic diseases that affect more than 90% of individuals during their lifetimes.1 Caused by inflammation of the pilosebaceous glands, acne vulgaris…

INTRODUCTION Long-term ultraviolet (UV) radiation facilitates the development of skin tumors. Lerche et al have reported that TCIs, including topical pimecrolimus and tacrolimus, did not accelerate photocarcinogenesis in hairless mice…

INTRODUCTION Flap viability depends on adequate blood flow in relation to the tissue-specific metabolic demands. Severed nutrient blood vessels and surgical denervation result in immediate reduction in perfusion pressure and…

INTRODUCTION Discoid lupus erythematosus (DLE) is a subtype of lupus erythematosus which presents mainly in areas above the neck include the nose, malar region, and ears.1 It is characterized clinically…

Duke Dermatology is a leader in advanced treatment of skin disease. The first Chief of Duke Dermatology was Dr. J. Lamar Callaway, a founding member of the Society of Investigative…

INTRODUCTION Antiphospholipid antibody syndrome (APS) can cause catastrophic thrombotic events, with cutaneous manifestations as the first sign of APS in up to 41% of patients.1 It is important to promptly…

INTRODUCTION Chemotherapy agents contribute to a number of side effects in the skin. This table highlights the major cutaneous adverse reactions in commonly used chemotherapy agents.DISCLOSURES The authors have disclosed…

INTRODUCTION It is well known that many disease processes manifest in areas of trauma. For example, psoriasis can occur in predisposed individuals from an inciting event such as an excoriation.…

INTRODUCTION Griscelli syndrome (GS) is a rare autosomal recessive disorder characterized by partial albinism, hepatosplenomegaly, pancytopenia, hepatitis, immunologic abnormalities, and lymphohistiocytosis.1 Here, we describe a case of Griscelli syndrome associated…

INTRODUCTION Radiation therapy is a commonly used and clinically important treatment for a variety of malignancies. The limiting factor in radiation treatment is often skin tolerance, as radiation injury to…

Spray-On Cell-Based Therapy and Leg Ulcers The results of a multicenter, phase-2 trial that shows the efficacy of a spray-on, cell-based treatment of venous leg ulcers was published August 2…

ACNE VULGARISA Randomized, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Gevokizumab in Subjects With Moderate to Severe Acne Vulgaris Sponsored by XOMA (US), LLC, the purpose of…