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Dec 10
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Split-Face Comparison of Ultrapulse-Mode and Superpulse- Mode Fractionated Carbon Dioxide Lasers on Photoaged Skin

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INTRODUCTIONAblative skin resurfacing (ASR) provides significant improvement in reversing signs of cutaneous photoaged skin1-6 but is limited by adverse postoperative sequelae such as extended recovery times, risk of infection, scarring,…
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Dec 10
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Treatment of Melasma and the Use of Intense Pulsed Light: A Review

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INTRODUCTION Melasma is a complex multifactorial disorder whose pathogenesis is not well understood. In addition to increased superficial and/or deep pigmentation, increased vascularity is often present. Vascular endothelial growth factor…
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Dec 10
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Treatment of Sebaceous Hyperplasia With a Novel 1,720-nm Laser

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INTRODUCTIONSebaceous hyperplasia is a common benign proliferation of sebaceous glands. Lesions are characterized by multiple lobules emptying into a large central duct. They normally present as round, yellow, umbilicated papules.1…
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Dec 10
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Treatment of Benign Pigmented Lesions Using a Long-Pulse Alexandrite Laser

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INTRODUCTIONTreatment of solar lentigines can be accomplished through several modalities, including the use of cryogen, hyfrecation, and light-based options. Based on the theory of selective photothermolysis,1 quality-switched (QS) lasers have…
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Dec 10
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Clinical Evaluation of the Safety and Efficacy of a Novel Superficial and Deep Carbon Dioxide Fractional System in the Treatment of Patients With Skin of Color

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INTRODUCTIONFractional laser therapy has become one of the mainstays of laser therapy around the world to treat a myriad of skin care concerns. Clinical evidence-based medicine has shown great success…
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Dec 10
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The Optimal Filler: Immediate and Long-Term Results With Emulsified Silicone(1,000 centistokes) With Cross-Linked Hyaluronic Acid

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INTRODUCTIONThe use of emulsified medical-grade silicone (Silikon®; Alcon Pharmaceuticals, Fort Worth, TX) with crosslinked hyaluronic acid (HA) is described. Previous studies have demonstrated the benefits of silicone fillers.1-5 More than…
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Dec 10
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Caffeine Protects Human Skin Fibroblasts From Acute Reactive Oxygen Species-Induced Necrosis

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INTRODUCTIONUltraviolet (UV) radiation generates hydrogen peroxide (H2O2) and other reactive oxygen species (ROS) that may result in damage to DNA, RNA, lipids, and proteins as well as cell death.1-4 Reactive…
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Dec 10
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Impact of Clobetasol Propionate 0.05% Spray on Health-Related Quality of Life in Patients With Plaque Psoriasis

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INTRODUCTIONPsoriasis is a highly visible skin disease, affecting approximately 2% to 3% of the U.S. population. It causes significant psychological and social distress and impairs health-related quality of life (HRQOL).1-3…
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Dec 10
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Resident Rounds. Part I: Program Spotlight: Virginia Commonwealth University Health System Department of Dermatology

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The Virginia Commonwealth University Health System (VCUHS) Department of Dermatology furnishes trainees with the educational and practical experience necessary to provide superior care of patients. Training is provided primarily at…
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Dec 10
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Surgical Corner: Wet Behind the Ears: The Postauricular Training Ground for Local Flaps

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BACKGROUNDA common obstacle in the training of dermatologic and plastic surgery fellows is taking the leap from theory to practice. While a reconstructive plan may seem forthcoming and easy to…
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Dec 10
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Resident Rounds. Part II: Molecular Basis for Selected Inherited Skin Disorders

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INTRODUCTIONThe molecular basis of many inherited skin disorders, or genodermatoses, has been described over the past several decades, leading to improved classification, description, and management of these diseases. In our…
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Dec 10
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Urticaria After Methyl Aminolevulinate Photodynamic Therapy in a Patient With Nevoid Basal Cell Carcinoma Syndrome

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INTRODUCTIONA 53-year- old Caucasian female with nevoid basal cell carcinoma syndrome (NBCCS) and a long-standing history of multiple basal cell carcinomas (BCCs) was referred to our practice after moving to…
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