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Dec 10
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Systemic Antioxidants and Skin Health

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INTRODUCTION Hippocrates said, "Let foods be thy medicine." Nutrition plays a key role in health and wellness. Poor nutrition contributes to aging and significantly increases the risk of developing systemic…
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Dec 10
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Microdermabrasion: Molecular Mechanisms Unraveled, Part 1

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INTRODUCTION Over the last few decades, multiple advancements in skin rejuvenation techniques have provided dermatologists with a myriad of options for enhancing the cosmetic appearance of skin. Most important, many…
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Dec 10
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Microdermabrasion: Molecular Mechanisms Unraveled, Part 2

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OVERVIEW AND TECHNIQUE Initially introduced in Italy in 1985, microdermabrasion (MDA) remains a popular cosmetic procedure today. The process involves rapid propulsion of abrasive microcrystals, usually aluminum oxide, at the…
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Dec 10
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Is White Coat Hypertension a Concern in Mohs Micrographic Surgery?

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INTRODUCTION White coat hypertension (WCHTN) refers to a clinical phenomenon characterized by elevated blood pressure (BP) when patients are in the doctor's office, where systolic BP ≥140 mm Hg, diastolic…
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Dec 10
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Effects of Oral Isotretinoin on Serum Folic Acid Levels

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INTRODUCTION Acne vulgaris is one of the most common dermatologic diseases that affect more than 90% of individuals during their lifetimes.1 Caused by inflammation of the pilosebaceous glands, acne vulgaris…
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Dec 10
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Topical Pimecrolimus 1% Reverses Long-term Suberythemal Ultraviolet B—induced Epidermal Langerhans Cell Reduction and Morphologic Changes in Mice

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INTRODUCTION Long-term ultraviolet (UV) radiation facilitates the development of skin tumors. Lerche et al have reported that TCIs, including topical pimecrolimus and tacrolimus, did not accelerate photocarcinogenesis in hairless mice…
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Dec 10
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Delay Techniques for Local Flaps in Dermatologic Surgery

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INTRODUCTION Flap viability depends on adequate blood flow in relation to the tissue-specific metabolic demands. Severed nutrient blood vessels and surgical denervation result in immediate reduction in perfusion pressure and…
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Dec 10
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In Vivo Reflectance Confocal Microscopy Features of Discoid Lupus Erythematosus

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INTRODUCTION Discoid lupus erythematosus (DLE) is a subtype of lupus erythematosus which presents mainly in areas above the neck include the nose, malar region, and ears.1 It is characterized clinically…
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Dec 10
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The Duke Dermatology Residency Training Program

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Duke Dermatology is a leader in advanced treatment of skin disease. The first Chief of Duke Dermatology was Dr. J. Lamar Callaway, a founding member of the Society of Investigative…
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Dec 10
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Antiphospholipid Antibody Syndrome Secondary to Trimethoprim/Sulfamethoxazole

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INTRODUCTION Antiphospholipid antibody syndrome (APS) can cause catastrophic thrombotic events, with cutaneous manifestations as the first sign of APS in up to 41% of patients.1 It is important to promptly…
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Dec 10
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Adverse Cutaneous Reactions to Chemotherapy Agents

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INTRODUCTION Chemotherapy agents contribute to a number of side effects in the skin. This table highlights the major cutaneous adverse reactions in commonly used chemotherapy agents.DISCLOSURES The authors have disclosed…
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Dec 10
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A Pathergic Response to Fractional CO2

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INTRODUCTION It is well known that many disease processes manifest in areas of trauma. For example, psoriasis can occur in predisposed individuals from an inciting event such as an excoriation.…
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