INTRODUCTION The relationship between mind and skin is essential and undeniable. From their common ectodermal embryologic origin, the nervous system and skin remain interconnected and communicate throughout life. The skin…

FDA Approval of CIP-ISOTRETINOIN Cipher Pharmaceuticals Inc. has announced that the FDA has approved AbsoricaTM, Cipher's novel, patented brand formulation of the acne medication isotretinoin, for the treatment of severe…

ROSACEA A Single Site Evaluation of the Effect of Topical Application of Aminocaproic Acid (ACA) to Inhibit Kallikrein 5 Serine Protease Activity and Production of LL-37 Cathelicidin Peptide, Biochemical Markers…

Flor A. Mayoral MDFlor A. Mayoral MD has been practicing in South Florida for 27 years. Dr. Mayoral is board certified by the American Academy of Dermatology (AAD) and the…

Just 10 years ago, studies were being published on biologics for psoriasis, new promising steps forward. At that time, one author wrote that biologics “provide only modest efficacy compared with…

INTRODUCTION The efficacy of ustekinumab in treating psoriasis has been demonstrated in Phase I through Phase III trials.1-6 Ustekinumab is a human monoclonal antibody that binds to the shared p40…

INTRODUCTION Janus kinases are a key component of the molecular machinery involved in signal transduction through various cytokine receptors.1 Janus kinases, which are associated with the cytoplasmic domain of cytokine…

INTRODUCTION Acne is a chronic condition with a prolonged course, slow onset, acute outbreaks, and a pattern of recurrence and relapse.1,2 Acne can have psychological and social consequences, 3 like…

INTRODUCTION Psoriasis is a T-lymphocyte (T-cell) mediated inflammatory skin disorder with an estimated prevalence of 1% to 3%,1 with up to one-third of affected individuals exhibiting moderate to severe disease.2…

INTRODUCTION Psoriasis is a common skin disease with a significant negative impact on health as well as quality of life and cumulative life course.1,2,3 In addition to systemic co-morbidities and…

INTRODUCTION Psoriasis is a chronic, inflammatory, immune-mediated disease of the skin that is often associated with co-morbidities such as depression, psoriatic arthritis, diabetes, and cardiovascular disease.1-5 Psychosocial co-morbidities, which may…

INTRODUCTIONPsoriasis is a chronic, genetically determined, immune-mediated inflammatory skin disease affecting approximately 2% to 3% of the Caucasian population. Plaque type is the most common form, even though other forms…