BACKGROUNDDermatofibrosarcoma protuberans (DFSP) is an uncommon dermal and subcutaneous neoplasm with a predilection for the trunk of young to middle-aged adults. The tumor presents clinically as solitary or multiple skin-colored,…
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INTRODUCTION Psoriasis is a chronic, immune-mediated, inflammatory skin disease that affects approximately 3% of the population in the United States (U.S.),1 or 6.4 million people.2 Recently, more emphasis has been…
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INTRODUCTION Pruritus is a common aspect of many conditions including urticaria, psoriasis, atopic dermatitis, renal failure and cholestasis. It is generally recognized that pruritus has a profound effect on quality-of-life…
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INTRODUCTIONPsoriasis is a chronic, immune-mediated, inflammatory condition that occurs worldwide; frequency varies greatly among different racial and ethnic groups.1,2 The prevalence of psoriasis has been estimated at 1.3 percent in…
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INTRODUCTION Psoriasis is caused by the interplay of various cellular processes in the skin, including keratinocyte hyperplasia, vascular proliferation and lymphocyte infiltration.1 Its multi-factorial etiology calls for many therapeutic agents…
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INTRODUCTION Etanercept is a fusion protein with affinity for soluble tumor necrosis factor alpha (TNF-a) that has been approved by the U.S. Food and Drug Administration (FDA) for the treatment…
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The Department of Dermatology at the University of California, San Francisco (UCSF), was founded in the early 1960s, and has grown to include close to 40 full-time faculty members and…
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INTRODUCTION Recent estimates suggest that psoriasis affects between two and 3.5 percent of adults in the United States (U.S.), which corresponds to approximately 4.5 million to 8 million adults.1,2 Scalp…
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ACKNOWLEDGEMENTS We thank Erin Mathes, MD, for reviewing the content of these tables.DISCLOSURES No outside funding was required for this manuscript. There are no commercial products discussed in this manuscript,…
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INTRODUCTION Seborrheic dermatitis (SD) is a common recurrent skin disorder characterized by erythema and scaling, with occasional papule and plaque formation and variable pruritus. The plaques of SD often appear…
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This trial was an investigator-initiated assessor blinded study of MetS and surrogate markers of increased CVD risk in pediatric psoriasis patients versus a control group of patients with warts. Our…
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INTRODUCTION Dermatomyositis is an idiopathic autoimmune disease, characterized by skin and skeletal muscle inflammation, which often presents in insidious fashion. Classic dermatologic findings include a violaceous heliotrope rash around the…
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