INTRODUCTIONRoflumilast is a topical phosphodiesterase-4 inhibitor (PDE-4i) approved by the Food and Drug Administration (FDA) for treating dermatological conditions, including plaque psoriasis and atopic dermatitis. The 0.15% formulation was approved…
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INTRODUCTIONMohs micrographic surgery (MMS) has emerged as a highly effective and precise treatment for skin cancer, offering exceptional cure rates while preserving healthy tissue.1 MMS involves the sequential removal of…
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INTRODUCTIONSun exposure is a risk factor for melanoma and non-melanoma skin cancer (NMSC),1,2 with NMSC being the cause of most skin cancer-related deaths.3 In addition, sun exposure contributes to photoaging,…
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INTRODUCTIONHair loss is a common dermatologic condition associated with significant psychosocial distress.1 It has been estimated that 50% of men and women suffer from the most common form of hair…
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INTRODUCTIONNicotinamide, also known as niacinamide, represents the water-soluble form of vitamin B3, while niacin, or nicotinic acid, constitutes its acidic counterpart. Nicotinamide plays a crucial role in our bodies by…
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CASE REPORTA 66-year-old woman with vulvar lichen sclerosis, Raynaud's phenomenon, and biliary colic status-post cholecystectomy presented for an intensely pruritic rash ongoing for several months. The eruption affected her right…
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INTRODUCTIONIn 2006, an article titled "Who benefits from calling a solar keratosis a squamous cell carcinoma" was published in the British Journal of Dermatology. The author, Robin Marks, expressed concern…
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INTRODUCTIONSignificant racial and ethnic disparities exist within dermatology, including a higher disease burden for numerous dermatologic conditions.1 Black and Hispanic/Latinx patients are more likely than White patients to delay care…
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INTRODUCTIONBenign Familial Pemphigus (Hailey-Hailey Disease ) is caused by a mutation within ATP2C1, the gene encoding the calcium pump of golgi apparatuses, impacting keratinocytes' ability to adhere to each other,…
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INTRODUCTIONSeborrheic dermatitis(SD) is a chronic inflammatory skin disease that affects sebaceous areas, typically the face and scalp, with an estimated prevalence of 2% to 5%. It is thought to result…
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INTRODUCTIONHidradenitis suppurativa (HS), or acne inversa, is a chronic inflammatory skin condition that is characterized by keratin and bacterial accumulation in hair follicles, leading to follicular rupture, abscess formation, and…
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BACKGROUNDRecent literature has suggested a link between dupilumab, a monoclonal antibody targeting receptors for interleukin (IL)-4 and IL-13, and cutaneous T-cell lymphoma (CTCL).1,2 Approved in 2017 for moderate to severe…
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