Narrow-Band Intense Pulsed Light as Treatment for Erythematotelangiectatic Rosacea: A Retrospective Study

November 2023 | Volume 22 | Issue 11 | 1095 | Copyright © November 2023


Published online October 20, 2023

doi:10.36849/JDD.4920

Hualing Shi BSN, Erjia Zhang MD, Mengli Zhang MD PhD, Tong Lin MD PhD

Department of Cosmetic Laser Surgery, Hospital for Skin Disease and Institute of Dermatology, Peking Union Medical College (PUMC) & Chinese Academy of Medical Sciences (CAMS), Nanjing, Jiangsu Province, China

Abstract
Background: Erythematotelangiectatic rosacea can be successfully treated using various laser and light-based devices. However, the use of narrow-band intense pulsed light for the treatment of erythematotelangiectatic rosacea has not been investigated in detail. This retrospective study aimed to analyze the clinical efficacy of narrow-band intense pulsed light (500-600 nm) for the treatment of erythematotelangiectatic rosacea among Chinese individuals. 
Methods: Patients with erythematotelangiectatic rosacea who had completed 3 sessions of treatment with narrow-band intense pulsed light and follow-up from July 2016 to December 2018 were retrospectively evaluated. Clinical improvement was assessed by 2 blinded dermatologists based on photographs obtained at each follow-up visit using the clinician erythema assessment scale and 5-grade scale.
Results: Forty-five patients with erythematotelangiectatic rosacea treated with narrow-band intense pulsed light were included in this study. The effectiveness and excellent rates after 3 treatment sessions were 68.9% and 35.6%, respectively. An average of 2 treatment sessions was required among patients who achieved good or excellent clearance of erythema and telangiectasia. Except for transient erythema and edema, no severe adverse effects were observed.
Conclusions: Narrow-band intense pulsed light is a safe and effective treatment for erythematotelangiectatic rosacea. Even with a small number of treatment sessions, narrow-band intense pulsed light can deliver a significant therapeutic effect, which may be applicable in clinical practice.

J Drugs Dermatol. 2023;22(11):1095-1098     doi:10.36849/JDD.4920

INTRODUCTION

Rosacea is a chronic inflammatory dermatosis that manifests as facial erythema, telangiectasia, papule, and pustule. Clinically, it can be classified into the following 4 common subtypes: erythematotelangiectatic rosacea (ETR), papulopustular rosacea, phymatous rosacea, and ocular rosacea.1 ETR is mainly characterized by flushing and persistent central facial erythema with or without telangiectasia. Associated secondary features, such as central facial edema, burning sensation, and scaling, may be present simultaneously.2 Moreover, persistent facial erythema is the most characteristic clinical manifestation of ETR that affects an individual’s appearance and has a significant psychosocial effect.3 Traditional medical therapies, such as topical and oral antibiotics are effective for ETR treatment; however, improvement in erythema and telangiectasia is limited.4 Recently, various laser and light-based devices, such as pulsed dye laser (PDL), potassium titanyl phosphate (KTP), intense pulsed light (IPL), and IPL combined with radiofrequency have been successfully used for the treatment of erythema and telangiectasia in patients with ETR.

Dye pulsed light (DPL)6 is a kind of narrow-band pulsed light technology, and it uses filters that concentrate the light into a narrow and specific spectrum (500-600 nm), which contains the absorption peak of melanin and hemoglobin. The output energy could accurately concentrate on the blood vessels and spots improving facial erythema and pigmentation more efficiently. In addition, compared with broadband IPL, the Dye-PL handpieces (Alma Lasers Ltd., Israel) provide optimum results without exposing the skin to wavelengths that may produce adverse effects. DPL provides an effective, non-invasive approach to vascular treatment. In this study, we aimed to retrospectively analyze the clinical efficacy of DPL (500-600 nm) in treating ETR in Chinese individuals.

MATERIALS AND METHODS

Patients
Patients clinically diagnosed with ETR and treated using DPL at the Hospital for Skin Disease and Institute of Dermatology, Peking Union Medical College (PUMC) & Chinese Academy of Medical Sciences (CAMS) from July 2016 to December 2018 were retrospectively evaluated. All patients who completed 3