Minocycline-Induced Hyperpigmentation Resolves during Oral Isotretinoin Therapy

December 2007 | Volume 6 | Issue 12 | Case Reports | 1232 | Copyright © December 2007

Jennifer Soung MD, Justine Cohen BA, Robert Phelps MD, Steven R. Cohen MD MPH

Although disfiguring hyperpigmentation is a well-defined complication of minocycline therapy, modalities to reverse the phenomenon are unpredictable. We report a case of minocycline-induced, blue-black pigmentation in a 23-year-old Hispanic man, which resolved after treatment with oral isotretinoin for acne vulgaris.