Induction of Lesional and Circulating Leukocyte Apoptosis by Infliximab in a Patient with Moderate to Severe Psoriasis

Infliximab demonstrates high efficacy in treating psoriasis in a high proportion of patients. In this report we demonstrate induction of plaque (T cells, dendritic cells) and peripheral blood (T cells, monocytes) leukocyte apoptosis following a single infliximab infusion in a psoriasis patient.