FULL SUPPLEMENT: Updating Antibiotic Use for Acne Management in 2023

February 2024 | Volume 23 | Issue 2 | SF378969s1 | Copyright © February 2024


Published online January 31, 2024

Naiem T. Issa MD PhDa, Leon H. Kircik MDb

aForefront Dermatology, Vienna, VA; Issa Research & Consulting, LLC, Springfield, VA;
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL
bIcahn School of Medicine at Mount Sinai, New York, NY; Indiana University Medical Center, Indianapolis, IN;
Physicians Skin Care, PLLC Louisville, KY; DermResearch, PLLC Louisville, KY; Skin Sciences, PLLC Louisville, KY

Abstract
Antibiotics, topical and oral, are a cornerstone in the treatment of acnes vulgaris specifically by targeting the skin bacterium Cutibacterium acnes. Billions of individuals have received antibiotics as part of their treatment resulting in a worldwide pandemic of antibiotic resistance not only for C. acnes but also many other pathogens. With the increasing prevalence of acne and exponentially increasing utilization of antibiotics, prescribers must urgently embrace the notion of antibiotic stewardship to maintain the efficacy of acne treatments while attenuating the rise of resistance. This paper serves as an update on C. acnes resistance to antibiotics commonly employed in the treatment of acne and the necessity of implementing benzoyl peroxide in the treatment regimen as monotherapy or combination antibiotic therapies for overcoming and preventing resistance.

J Drugs Dermatol. 2024;23:1(Suppl 2):s4-10.
In this supplement:

Vehicles Matter!
Cutibacterium acnes (C. acnes, formerly Propionibacterium acnes), the bacterium that lends its name to one of the most common dermatologic conditions, has been studied for decades. Yet science continues to uncover discoveries about this ubiquitous, commensal organism and the pathogenesis of acne vulgaris.

Read the article here.

Antibiotic Stewardship in Acne: 2023 Update
Antibiotics, topical and oral, are a cornerstone in the treatment of acnes vulgaris specifically by targeting the skin bacterium Cutibacterium acnes. Billions of individuals have received antibiotics as part of their treatment resulting in a worldwide pandemic of antibiotic resistance not only for C. acnes but also many other pathogens.

Read the article here.