In this supplement
Psoriasis Is a Systemic Disease
Obesity in the US is a significant public health concern. According to the CDC, 22 states have an adult obesity prevalence of 35 percent or higher. Obesity is a proinflammatory state and is associated with increased risk for cardiovascular disease, diabetes mellitus, certain malignancies, musculoskeletal diseases, and liver disease, as well as psychiatric effects and decreased life expectancy.
Read the article here.
Obesity is a metabolic disease that is marked by excessive fat accumulation and is objectively defined as a body mass index (BMI) greater than or equal to 30 kg/m2. Obesity is associated with several other comorbidities, including psoriasis, which is a chronic autoimmune skin disease. Adipocytes produce pro-inflammatory signaling molecules, namely adipokines and classic cytokines, that drive increased inflammation and may contribute to the pro-inflammatory pathways driving psoriasis disease pathogenesis.
Psoriasis and Obesity: Optimizing Pharmacologic Treatment
Obesity is a metabolic disease that is marked by excessive fat accumulation and is objectively defined as a body mass index (BMI) greater than or equal to 30 kg/m2. Obesity is associated with several other comorbidities, including psoriasis, which is a chronic autoimmune skin disease. Adipocytes produce pro-inflammatory signaling molecules, namely adipokines and classic cytokines, that drive increased inflammation and may contribute to the pro-inflammatory pathways driving psoriasis disease pathogenesis.
