Dyshidrotic-like Spongiotic Dermatitis after Intravenous Immunogolulin Therapy

June 2003 | Volume 2 | Issue 3 | Case Reports | 337 | Copyright © June 2003

Hendrik Uyttendaele, Md, PhD; Joseph Obadiah, MD and Marc Grossman, MD

Intravenous immunoglobulin (IVIG) therapy has been used to treat a variety of immune mediated disorders. Cutaneous reactions to IVIG are rare and have only been anecdotally described. We describe three cases with dyshidrotic-like biopsy proven spongiotic dermatitis after administration of IVIG. These three cases may highlight an uncommon and rarely reported side effect of IVIG.