Impact of Iron-Oxide Containing Formulations Against Visible Light-Induced Skin Pigmentation in Skin of Color Individuals

July 2020 | Volume 19 | Issue 7 | Original Article | 712 | Copyright © July 2020

Published online June 18, 2020

Hawasatu Dumbuya PhDa, Pearl E Grimes MDb, Stephen Lynch PhDa,b, Kalli Ji PhDa, Manisha Brahmachary PhDa, Qian Zheng Md PhDa, Charbel Bouez PhDa, Janet Wangari-Talbot PhDa

aL’Oréal Research and Innovation, Clark, NJ bVitiligo & Pigmentation Institute, Los Angeles, CA

protection, and development of standardized guidelines for in vivo assessments of VL-PF and interpretation of this value.


In summary, our results show that products containing FeO protect the skin from VIS-induced pigmentation better than a mineral SPF50+ sunscreen containing TiO2 and ZnO. These findings highlight that FeO pigments-based foundation formulations can play a dual role by camouflaging existing pigmentation, as well as reducing the development of pigmentation triggered by sun exposure. The rising evidence that VIS and IR can induce long lasting biological responses in human skin has created the need to find non-traditional strategies for full spectrum photoprotection and beyond the UV range. Moreover, it is essential to identify different ways to bring clinically visible benefits that are compatible to daily routines of patients for minimizing the damaging effects of chronic sun exposure. The availability of topical products containing pigments and/or metal oxides, such as foundations in multiple shades and tones, can offer customized daily protection beyond UV for individuals of all skin phototypes.


Pearl Grimes serves as a consultant for VT Cosmetics, Incyte and Dermaforce; as an investigator for Aclaris Therapeutics, Allergam, Pfizer, L’Oreal, Johnson & Johnson, Clinuvel, Thync Global Inc., VT Cosmetics and Incyte. All other authors are employees of L’Oreal Research & Innovation, USA.


We thank Anil Shah for obtaining the absorbance spectra of test products, Dr. Kumar Pillai for critical reading of the manuscript, and Dermablend Professional for providing full coverage foundations.


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Janet Wangari-Talbot PhD