Extracellular Matrix Modulation: Optimizing Skin Care and Rejuvenation Procedures openaccess articles

April 2016 | Volume 15 | Issue 4 | Supplement | s64 | Copyright © 2016


Similar to how the chronic wound healing process requires wound bed preparation before therapeutic intervention, treatment of chronic aging of the skin would likely benefit from a “skin bed preparation” to optimize the outcome of rejuvenation procedures and skin maintenance programs. This involves introducing agents that can combat stress-induced oxidation, proteasome dysfunction, and non-enzymatic cross linkages involved in glycation end products, to collectively modulate the damaged extracellular matrix, and upregulate neocollagenesis and elastin production.

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