Acne Quality of Life and Patient Satisfaction Following Treatment With Tretinoin Pump
December 2009 | Volume 8 | Issue 12 | Original Article | 1080 | Copyright © December 2009
Richard Fried MD PhD and Marge Nighland BS
Patient satisfaction and quality of life are important considerations when assessing products used to treat acne vulgaris, as these
factors may affect treatment adherence and subsequent treatment outcomes. The objective of this analysis was to determine patient
satisfaction and improvement in quality of life after treatment with tretinoin gel microsphere (TGM) in a pump dispenser. Assessments
were made during a phase IV, prospective, 12-week, open-label, community-based trial in which 544 patients who were dissatisfied
with their current acne treatments received TGM 0.04% or 0.1% in addition to ≤ 2 concurrent non-retinoid acne therapies.
At week 12, significant improvement was reported in both patient acne therapy satisfaction and in the overall mean Acne Quality
of Life Index scale15 (P<0.0001 versus baseline for both measures). The majority of patients (82.3%) rated the pump dispenser as
an “excellent” or “very good” means of dispensing medication, and 86.0% rated their overall satisfaction with the pump treatment
application as “very satisfied” or “extremely satisfied.” The results of this study indicate that the use of TGM in a pump dispenser in
patients with acne vulgaris is associated with significant increases in both quality of life and patient satisfaction.