The Utility of Benzoyl Peroxide in Hydrophase Base (Brevoxyl®) in the Treatment of Acne Vulgaris
April 2006 | Volume 5 | Issue 4 | Original Article | 344 | Copyright © April 2006
Jeffrey M. Weinberg MD
Benzoyl peroxide in hydrophase base (Brevoxyl® Creamy Washes and Gels) has shown significant efficacy in the treatment of acne, with lower irritancy than other benzoyl peroxide preparations. It is felt that the low irritancy of this product is related to a unique delivery vehicle containing dimethyl isosorbide, which dissolves benzoyl peroxide crystals on the skin. Clinical studies demonstrating the efficacy and safety of benzoyl peroxide in hydrophase base will be reviewed.