Phosphatidylcholine in the Treatment of Localized Fat
October 2003 | Volume 2 | Issue 5 | Original Article | 511 | Copyright © October 2003
Doris Hexsel, MD; Marcio Serra, MD; Rosemari Mazzuco, MD; Taciana Dal'Forno, MD and Debora Zechmeister, RPh
Phosphatidylcholine was initially used in emergencies and in the treatment of atheroma plaques in cardiac diseases.
Recently, it has also been used in the treatment of localized fat deposits. We report on the authors’ clinical
experience of the use of 250 mg/ml phosphatidylcholine injections in the treatment of subcutaneous fat
deposits, showing the clinical response and side-effects. Volunteers received phosphatidylcholine injections in
several areas of localized fat deposits, with a minimum interval of one week and mean interval of 15 days
between applications. Laboratory tests were performed during the period of the drug use. Clinical results
reflect that phosphatidylcholine was efficacious in reducing the fatty pads in the treated areas, with few side
effects. From the authors’ point of view, the off-label use of phosphatidylcholine in the treatment of fatty pads
and small areas of localized fat is safe, low cost, and effective.