Diffuse Ulcerations Due to Disseminated Histoplasmosis in a Patient with HIV
March 2003 | Volume 2 | Issue 2 | Case Reports | 189 | Copyright © March 2003
Noah Scheinfeld, MD
Histoplasmosis is a well-described opportunistic infection that accompanies human-immunodeficiency virus (HIV) infection. We report an unlikely victim of disseminated histoplasmosis who suffered this infection while on antiretroviral therapy and with a CD-4 count of 525/mm3. Notably, he had a normal chest x-ray and disseminated cutaneous ulcers. The diagnosis was made by skin biopsy, and his infection responded promptly to itraconazole therapy. This case serves as a reminder that the immunological derangements and cutaneous alterations wrought by HIV remain unpredictable in nature and extent.