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Apr 30
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Longer Pembrolizumab Therapy Reduces Mortality in Stage III and IV Melanoma: A TriNetX Study

By Chuck Lin No Comments
INTRODUCTIONMelanoma is the leading cause of skin cancer-related mortality worldwide.¹ Advances in anti-programmed cell death protein 1 (PD-1) therapies, such as pembrolizumab, have significantly improved survival outcomes in advanced melanoma.²…
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Apr 30
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Efficacy and Safety of Topical Metformin vs Kligman Formula in the Treatment of Melasma: A Split-Face Study

By Chuck Lin No Comments
INTRODUCTIONMelasma is a frequent chronic pigmentary condition that is resistant to treatment, most commonly affecting Fitzpatrick skin types III to V.1 Worldwide, melasma is one of the most prevalent dermatoses,…
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Apr 30
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Safety and Efficacy of Aminolevulinic Acid 20% Topical Solution Activated by Blue Light for Facial Cutaneous Squamous Cell Carcinoma in situ

By Chuck Lin No Comments
INTRODUCTIONNonmelanoma skin cancer is the most common form of cancer, with cutaneous squamous cell carcinoma (SCC) accounting for more than 20% of all skin cancers.1,2 Although historically less prevalent than…
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Apr 30
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Advances in Gentle Polymeric Cleansing Technologies

By Chuck Lin No Comments
INTRODUCTIONThe primary goal of a skin cleanser is to remove surface dirt, sweat, sebum, and contaminants without irritating or drying the skin. The key ingredients in cleansers include surfactants for…
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Apr 30
Love0

Efficacy and Safety of Cosibelimab for Advanced Cutaneous Squamous Cell Carcinoma: An Expert Consensus Panel

By Chuck Lin No Comments
INTRODUCTIONCutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer, with increasing incidence rates worldwide.1 While most cases are successfully treated with surgical excision or radiation therapy, a…
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Apr 30
Love0

Time is Tissue: A Representative Case Report Highlighting the Importance of Early Clinical Diagnosis of Necrotizing Fasciitis

By Chuck Lin No Comments
INTRODUCTIONNecrotizing fasciitis is an uncommon but potentially rapidly fatal infection. The mortality rate is estimated to be 23-29%1 and when it affects the limbs, the amputation rate is 11-14%.1 There…
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Apr 30
Love0

Malassezia Folliculitis Presentation, Diagnosis, and Treatment: A Review of “Fungal Acne”

By Chuck Lin No Comments
INTRODUCTIONMalassezia folliculitis (MF) is a lipid-dependent fungus that thrives on the lipid composition of sebum in the sebaceous glands of hair follicles and the stratum corneum.1,2 Malassezia was previously referred…
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Apr 30
Love0

INDIVIDUAL ARTICLE: Clinical and Real-World Implications of IL-17 Receptor Blockade in Plaque Psoriasis and Psoriatic Arthritis With Brodalumab

By Chuck Lin No Comments
INTRODUCTIONPsoriasis is a chronic immune-mediated inflammatory disease driven by dysregulated interleukin-17 (IL-17) signaling across skin and musculoskeletal tissues. While upstream IL-23 inhibition and selective IL-17 cytokine blockade have improved outcomes,…
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Apr 30
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FULL SUPPLEMENT: Mechanism Matters: IL-17 Receptor Blockade With Brodalumab and Its Role in Durable Psoriasis Clearance and Fast Onset of Action

By Chuck Lin No Comments
In this issue:Clinical and Real-World Implications of IL-17 Receptor Blockade in Plaque Psoriasis and Psoriatic Arthritis With BrodalumabBrodalumab is a fully human monoclonal antibody targeting interleukin-17 receptor A (IL-17RA), providing…
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Apr 29
Love0

Dermatologists’ Practices and Perspectives on HPV, Surgical Plume, and Cancer Risk

By Chuck Lin No Comments
INTRODUCTIONThis is the first study to examine HPV vaccination rates, protective equipment use, and self-reported health outcomes among dermatologic surgeons in the context of surgical plume exposure. Dermatologists routinely perform…
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Apr 29
Love0

Pembrolizumab as an Off-Label Treatment of Facial Angiosarcoma: A Case Report

By Chuck Lin No Comments
INTRODUCTIONCutaneous angiosarcoma is a rare, aggressive malignant neoplasm of vascular endothelial cell origin with a poor prognosis, due to its rapid growth and propensity for local recurrence and distant metastasis.1,2…
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Apr 29
Love0

Treatment of Confluent and Reticulated Papillomatosis Using Fixed-Dose Clindamycin phosphate 1.2%/Adapalene 0.15%/Benzoyl Peroxide 3.1% Gel

By Chuck Lin No Comments
INTRODUCTIONConfluent and reticulated papillomatosis (CARP) is a chronic dermatologic condition characterized by multiple hyperpigmented papules that converge to form plaques or patches and reticulate peripherally. The etiology of CARP remains…
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