Dear Editor, Keloids are a dermatologic condition with high recurrence rates and variable treatment success. Racial disparities can play a crucial role in diagnosis delays and treatment outcomes. Studies have…
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INTRODUCTIONPhysical characteristics that can contribute to gender dysphoria in transgender patients, including facial and body hair, hormonal acne, and post-surgical scarring, can be addressed through dermatologic interventions.1,2 While perceived gender-incongruence…
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INTRODUCTIONCutis marmorata telangiectatica congenita (CMTC) is a rare congenital vascular disorder characterized by violaceous, reticulated skin that may be complicated by painful ulcerations. Limited presentations often improve but rarely fully…
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INTRODUCTIONAndrogenetic alopecia (AGA) is a non-scarring alopecia triggered by an inherited follicular sensitivity to dihydrotestosterone (DHT) and other environmental factors.1 Current FDA-approved treatments include topical minoxidil (in men and women)…
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INTRODUCTIONPsoriatic disease is a common chronic immune-mediated systemic inflammatory disease, most often presenting as chronic plaque psoriasis with erythematous, scaly lesions that cause pain, pruritus, and cosmetic burden.1 The pathophysiology…
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INTRODUCTIONPsoriasis is a chronic immune‑mediated inflammatory skin disease that is strongly associated with metabolic dysregulation and excess adiposity.1 Adipose tissue dysfunction contributes to systemic inflammation, promoting Th17/IL‑17 pathways that drive…
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INTRODUCTIONWith an estimated global prevalence of >9% across all ages, acne vulgaris is one of the most common skin disorders.1 However, acne prevalence among adults may be increasing, particularly for…
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INTRODUCTIONMolluscum contagiosum (MC), caused by the molluscum contagiosum virus (MCV), is a cutaneous infection that commonly affects children.1 Molluscum can significantly impair quality of life, contributing to social stigma, discomfort,…
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INTRODUCTIONPsoriasis is a chronic inflammatory condition affecting the skin.1,2 Pathophysiology involves Th1- and Th17-driven inflammation with consequently increased levels of TNF-α, IL-17, and IL-23.3 Patients with psoriasis are at increased…
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INTRODUCTIONRosacea is a chronic inflammatory facial skin condition characterized by episodic or persistent erythema, edema, telangiectasias, and/or inflammatory papules and pustules.1 The global prevalence of rosacea is approximately 5.46%, with…
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INTRODUCTIONGeneralized pustular psoriasis (GPP) is a rare, chronic, severe autoinflammatory dermatosis distinguished by abrupt flares of sterile pustulation, systemic inflammation, and substantial morbidity and mortality.1-4 Once viewed as a variant…
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In this issue:Generalized Pustular Psoriasis: A Contemporary Review of Diagnosis, Pathophysiology, and IL-36 Pathway–Directed ManagementGeneralized pustular psoriasis (GPP) is a rare, chronic, severe autoinflammatory dermatosis distinguished by abrupt flares of…
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